Articles

A Single-Center Retrospective Study on the Effects of Korean Medicine in 342 Traffic Accident Cases
1Jisung-Kyunghee Korean Medicine Clinic, Seoul, Republic of Korea
2Bogwang Korean Medical Clinic, Seoul, Republic of Korea
3Department of Acupuncture & Moxibustion Medicine, College of Korean Medicine, Gachon University, Seongnam, Republic of Korea
Correspondence to:Ji Hye Hwang
Department of Acupuncture & Moxibustion Medicine, College of Korean Medicine, Gachon University, Seongnam 13120, Republic of Korea
Tel: +82-32-770-1342
E-mail: jhbori@nate.com
This is an Open-Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
J Pharmacopuncture 2021; 24(3): 122-137
Published September 30, 2021 https://doi.org/10.3831/KPI.2021.24.3.122
Copyright © The Korean Pharmacopuncture Institute.
Abstract
Methods: We retrospectively surveyed the medical charts of 342 traffic accident patients treated at the Jisung KM clinic between January 2009 and June 2017.
Results: Most of the patients were men and in their 30s. The most common method of locating the clinic was an internet search. The most common traffic accident type was collision between vehicles (83.63%), with 70.76% of patients visiting during the most acute phase. The major disease codes included S434, M4836, F072, S0600, and S3350. The most frequent treatment period was within 1 month of the accident, and most patients received 10 or fewer treatments. The mean treatment duration and number of treatments were 37.68 ± 45.11 days and 11.68 ± 10.63 treatments, respectively. The initial pain numerical rating scale (NRS), 7.32 ± 0.96, decreased to 3.57 ± 1.40 at the end of treatment, with a symptom improvement score of 1.87 ± 0.60. Regarding sex, age, disease duration, location at the time of the accident, presence of additional and psychological symptoms, and chuna, there were statistically significant differences in treatment duration and number of treatments. A higher number of treatments and the longer treatment duration was associated with a higher initial NRS, lower post-treatment NRS, and better improvement score. Since the introduction of traffic accident (TA) pharmacopuncture, the rate of use of a single type of pharmacopuncture increased; however, no significant differences in treatment duration and number, NRS before and after treatment, and improvement score were observed between treatment groups before and after TA pharmacopuncture. No adverse reactions were observed for any treatment.
Conclusion: This study confirmed the previous findings of a high treatment effect of KM under automobile insurance. We also observed significant correlations based on a detailed medical status, which may explain the increasing use of KM in the automobile insurance system. Additional multi-center studies in different regions are needed.
Keywords
INTRODUCTION
Traffic accident injuries are common and can cause unexpected pain and functional decline [1]. The estimated associated annual costs after road accidents in 2016 exceeded £35 billion in the United Kingdom and exceeded USD 21 billion in South Korea, accounting for approximately 1.4% of the gross domestic product [2, 3]. As traffic accidents cause serious socioeconomic problems worldwide, the management of injuries and aftereffects of traffic accidents has become an important issue.
In South Korea, traditional Korean medicine (TKM) techniques, such as acupuncture and herbal medicine, along with chuna manual therapy, pharmacopuncture, and physical therapy are now included in the automobile insurance coverage and are provided to traffic accident patients [4]. According to the Automobile Insurance Statistical Data from the Health Insurance Review & Assessment Service, TKM automobile insurance medical expenses doubled, from KRW 357.8 billion in 2015 to KRW 713.9 billion in 2018. In addition, a 21% increase in the number of patients at TKM institutions was reported, compared to a 1% increase at western medicine (WM) institutions [5].
Traffic accident patients have more mild injuries such as simple sprains and concussions than severe injuries, and most patients complain of neck and back pain [6]. Sprains of the cervical and lumbar spine show no major abnormalities in radiological assessments, and many patients prefer TKM for conservative treatment [7].
In 2018, medical expenses associated with TKM, including at 295 TKM hospitals and 11,582 TKM clinics, increased by 28.76% year-on-year to KRW 713.9 billion. In particular, TKM clinics accounted for the largest percentage of the 19,650 medical institutions providing automobile insurance and ranked first in the total number of claims and total care costs for automobile insurance [5].
Owing to the rapid growth of the TKM automobile insurance market, data on satisfaction and improvement following TKM treatment have been collected [6, 8]; however, there are few reports on the status of automobile insurance treatments at TKM clinics [9]. Therefore, additional reports on the medical status at TKM clinics are needed. Thus, this study retrospectively analyzed the current status and effect of automobile insurance TKM treatment in a single TKM clinic and verified the justification for TKM treatment under automobile insurance.
MATERIALS AND METHODS
1. Subjects
This study included 342 of 385 patients who received outpatient treatment at Jisung Kyunghee TKM Clinic for traffic accident injuries between January 1, 2017, and June 30, 2019, except for 43 patients who did not find accurate treatment results. The 43 excluded patients included 26 who received fewer than two treatments, two for whom improvement could not be confirmed in the chart records, two who were treated once in our clinic and in another clinic for several months, four who visited more than 6 months after the accident, eight under 19 years of age, and one who received only four treatments in preparation for pregnancy after abortion. This study was a retrospective review of the charts of patients who provided informed consent and was approved by the Institutional Review Board of Gachon University Korean Medical Hospital (IRB No. M-19-123).
2. Research method
The 342 cases were examined for overall medical treatment status according to sex and age, accident type, disease duration, symptoms and diagnosis, and treatment duration and frequency. We analyzed the treatment duration and frequency, pain numerical rating scale (NRS) before and after treatment, and symptom improvement score according to sex and age, accident type, disease duration, additional symptoms and psychological symptoms, and chuna treatment. We also analyzed the status of patients who received pharmacopuncture and investigated the treatment response and adverse events during the treatment period.
3. Evaluation of treatment grade and symptom improvement
The pain index used in this study was the NRS. The initial NRS was defined as the most severe pain immediately after the accident, while the late NRS was that at the end of treatment. Subjective symptom improvement was classified into four stages: (1) Excellent (no functional impairment due to normal recovery of subjective symptoms and physical examination), (2) good (subjective symptoms and physical examination showed clear improvement compared to those in the first visit), (3) fair (improvement or slight improvement on subjective symptoms and physical examination), and (4) poor (no improvement or worsened condition on subjective symptoms and physical examination) using Odom’s criteria [8-11] and a score of 1-4 points using a Likert four-point scale.
4. Intervention
Acupuncture was performed for 15 minutes with disposable stainless needles (0.25 mm in diameter and 40 mm in length, Dong Bang, Boryeong, Korea) at a depth of 10-30 mm, depending on the insertion site. The acupoints were mainly the GB20, GV17, GB21, GV4, GV3, BL23, GV30, and ouch points (ashi points). According to the patient’s symptoms, electro-acupuncture stimulation, cupping, pharmacopuncture, and chuna manual therapy were combined. In cases requiring drug treatment, concussion symptoms were first treated with a concussion prescription, which is a combination of Dohongsamultang and BanhabaekchulcheonMatang; in addition, Hwaeojeon-gami prescription was used for trauma blood stasis. Physiotherapy was performed once daily, mainly using interferential current therapy and a hot pack according to the patient’s condition.
5. Safety and adverse reactions to treatment
Immediately after each treatment and at the next visit, we checked for bleeding, hematoma, fatigue, sweating, severe nausea, dizziness, and headache, as well as infections and patient discomfort related to treatments such as acupuncture, pharmacopuncture, herbal medicine, and chuna treatment.
6. Statistical analysis
The statistical analyses were performed using IBM SPSS Statistics for Windows, version 25.0. Relationships between the treatment period and number, NRS before and after treatment, and symptom improvement for each factor were assessed by independent two-sample t-tests for two groups and one-way analysis of variance (ANOVA) for three or more groups. The correlations between the treatment duration, number of treatments, NRS before and after treatment, and improvement were evaluated by Pearson’s correlation analysis. p < 0.05 was considered statistically significant.
RESULTS
1. Distribution by sex, age, visit motivation, and disease duration
The study population was composed of 1.51 times more men (n = 209, 61.11%) than women (n = 138, 38.99%). The age distribution was as follows: individuals in their 20s (n = 72, 21.05%), 30s (n = 137, 40.06%), 40s (n = 79, 23.10%), 50s (n = 36, 10.53%), and 60s or older (n = 18, 5.26%). The most common motivations for visiting the clinic were an internet search (197 patients, 57.60%), followed by previous treatment at our clinic (70 patients, 20.47%), introduction by acquaintances (36 patients, 10.53%), proximity (35 patients, 10.23%), and other reasons (4 patients, 1.17%). Most patients (242, 70.76%) visited during the most acute phase (within 1 week); 87 patients (25.44%) visited in the acute phase (1 week-1 month) and 13 patients (3.80%) visited during the subacute stages (1-6 months after onset) (Table 1).
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Table 1 . Patient characteristics.
Characteristics Sex Total
number (%)Male Female Age group (years) < 30 35 (10.23) 37 (10.82) 72 (21.05) 30 ≤, < 40 97 (28.36) 40 (11.70) 137 (40.06) 40 ≤, < 50 52 (15.20) 27 (7.89) 79 (23.10) 50 ≤, < 60 20 (5.85) 16 (4.68) 36 (10.53) 60 ≤ 5 (1.46) 13 (3.80) 18 (5.26) Motivation for visiting Web search 120 (35.09) 77 (22.51) 197 (57.60) Current patient 42 (12.28) 28 (8.19) 70 (20.47) Acquaintance introduction 22 (6.43) 14 (4.09) 36 (10.53) Close distance 23 (6.73) 12 (3.51) 35 (10.23) Other 2 (0.58) 2 (0.58) 4 (1.17) Duration between
accident and visiting
our clinicWithin 1 week Accident day 19 (5.56) 9 (2.63) 242 (70.76) 1-2 days 82 (23.98) 31 (9.06) 3-7 days 54 (15.79) 37 (10.82) 1 week-1 month (Acute stage) 46 (13.45) 41 (11.99) 87 (25.44) 2-6 months (Subacute stage) 8 (2.34) 5 (1.46) 13 (3.8) Patterns of visiting
our clinicVia other
medical institutionTKM Outpatient 2 (0.58) Radioactive examination & TKM outpatient 2 (0.58) TKM hospital inpatient with radioactive examination 11 (3.22) WM Radioactive examination 52 (15.20) Discharge after admission and treatment 35 (10.23) Radioactive examination & WM outpatient 106 (30.99) Direct visit 134 (39.18) TKM, traditional Korean medicine; WM, Western medicine..
2. Distribution of patterns of visiting our clinic
A total of 134 patients (39.18%) visited our clinic without visiting other hospitals, while 208 (60.82%) visited our clinic after visiting another hospital. Among patients who visited WM institutions, 52 (15.20%) received only physical and radiological examinations without treatment, 35 (10.23%) visited our clinic after inpatient treatment at WM hospitals, and 106 (30.99%) visited our clinic after examination and outpatient treatment at WM clinics. Among patients who visited KM institutions, 11 (3.22%) were hospitalized with radiological examinations and two (0.58% each) visited our clinic after visiting another KM clinic with or without radiological examination (Table 1).
3. Distribution according to traffic accident characteristics
Among the accident types, 286 cases (83.63%) were caused by collisions between vehicles. Among them, 218 (63.74%), 36 (10.53%), 14 (4.09%), and 18 (5.26%) cases were rear, lateral, forward, and multiple collisions, respectively. Furthermore, 23 accidents were between vehicles and pedestrians (6.73%), 24 were between vehicles and motorcycles (7.02%), three were between vehicles and bicycles (0.88%), and six occurred while on a bus (1.75%). The distribution according to the location at the time of the accident included 257 cases in driver seats (75.15%), 17 in passenger seats (4.97%), 12 in back seats (3.51%), 23 pedestrians (6.73%), 27 motorcycles or bicycles (7.89%), and five bus passengers (0.39%) (Table 2).
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Table 2 . Distribution of traffic accident characteristics, symptoms, and disease codes.
Characteristics Total number (%) Traffic accident
characteristicsTraffic accident patterns Car to car Rear impact 218 (63.74) Frontal impact 14 (4.09) Side impact 36 (10.53) Multiple impact 18 (5.26) Pedestrian 23 (6.73) Car to motorbike 24 (7.02) Car to bicycle 3 (0.88) On the bus 6 (0.39) Location Driver’s seat 257 (75.15) Passenger seat 17 (4.97) Back seat 12 (3.51) Pedestrian 23 (9.30) Motorbike, bicycle 27 (7.89) Bus 6 (0.39) Symptoms* Physical symptoms Localized pain Neck & shoulder 297 (86.84) Low back & buttocks 306 (89.47) Head 202 (59.06) Knee & ankle 21 (6.14) Elbow & wrist 9 (2.63) Other 5 (1.46) Limb numbness 78 (22.8) Dizziness 156 (45.6) Fatigue 40 (11.7) Psychological symptoms Sleep disorder 41 (12.0) Chest discomfort due to stress 19 (5.7) Palpitations 16 (4.7) Disease code* S434: Sprain and strain of the shoulder joint 259 (75.73) M4836: Traumatic spondylopathy, lumbar region 224 (65.50) F072: Post-concussion syndrome 113 (33.04) S0600: Concussion, without an open intracranial wound 71 (20.76) S3350: Sprain and strain of the lumbar spine 66 (19.30) *Multiple choices were allowed for ‘symptoms’ and ‘disease code’..
4. Distribution according to symptoms and diagnosis
The symptoms were divided into physical and psychological symptoms. The major physical symptoms were localized pain in all patients, including 306 (89.47%) patients with pain in the lumbar and pelvic region, 297 (86.84%) with pain in the cervical spine and shoulders, 202 (59.06%) with headaches, 21 (6.14%) with pain in the knee and ankle, 9 (2.63%) with pain in the wrist and elbow, and 5 (1.46%) with other symptoms. Dizziness, limb numbness, and fatigue were reported in 156 (45.6%), 78 (22.8%), and 40 (11.7%) cases, respectively. Other symptoms included tinnitus, jaw joint problems, and digestive problems. The major psychological symptoms were sleep disorders (41 cases, 12.0%), chest discomfort (19 cases, 5.7%), palpitations (16 cases, 4.7%), followed by a sign of surprise, memory disorders, emotional control disorders, anxiety, depression, stress, and other symptoms.
Among disease code distributions, duplication of cases with two or more diagnosed cases showed sprain to be the most common, with the major disease codes being S434 (sprain and strain of shoulder joint), M4836 (traumatic spondylopathy, lumbar region), F072 (postconcussional syndrome), S0600 (concussion, without open intracranial wound), and S3350 (sprain and strain of the lumbar spine) (Table 2).
5. Distribution according to treatment duration and number of treatments
A total of 218 patients (63.74%) sought treatment within 1 month, including 57 patients (20.46%) within 2 weeks, 64 (18.71%) within 1 month, 44 (12.87%) within 3 weeks, and 40 (11.70%) within 1 week. Furthermore, 67 (19.59%) patients sought treatment within 2 months, 29 (8.48%) within 3 months, 10 (2.92%) within 4 months, and 18 (5.26%) after 4 months or more. Most patients (204, 59.65%) received fewer than 10 treatments; 90 (16.67%), 27 (7.89%), and 21 (6.14%) patients received fewer than 20, fewer than 30, and more than 30 treatments, respectively (Table 3).
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Table 3 . Distribution of treatment duration, number of treatments, and treatment method.
Characteristics Total number (%) Treatment duration ≤ 1 week 40 (11.70) ≤ 2 weeks 57 (20.46) ≤ 3 weeks 44 (12.87) ≤ 1 month 64 (18.71) ≤ 2 months 67 (19.59) ≤ 3 months 29 (8.48) ≤ 4 months 10 (2.92) ≥ 4 months 18 (5.26) Number of treatments ≤ 10 204 (59.65) ≤ 20 90 (16.67) ≤ 30 27 (7.89) 30 < 21 (6.14) Treatment method Acupuncture 341 (99.71) Herbal medicine 251 (73.39) Pharmacopuncture Total pharmacopuncture types
used for treatment1 126 (36.84) 2 109 (31.87) ≥ 3 105 (30.70) Type of pharmacopuncture TA 180 (58.44) HO 119 (38.64) CH 87 (28.25) MOK 85 (27.60) Others 46 (13.45) Chuna 153 (44.74) TKM physiotherapy 298 (87.13) TKM, traditional Korean medicine; TA, a pharmacopuncture medicine which was named after traffic accidents and consists of Scutellaria baicalensis, Phellodendron amurense, Pulsatilla koreana, Sophorae Tonkinensis Radix et Rhizoma, Aucklandia lappa, and Carthamus tinctorius L.; HO, a pharmacopuncture medicine which was named after Honghwaja (Carthamus tinctorius L); CH, a pharmacopuncture medicine which was named after channel, developed to control pain using sodium channels by adding salt and consists of Moschus, Ursi Fel, Bovis Calclus, Scutellaria baicalensis, Phellodendron amurense, Pulsatilla koreana, Sophorae Tonkinensis Radix et Rhizoma, Aucklandia lappa, and salt; MOK, a pharmacopuncture medicine which was commonly used to treat clinical symptoms related to heart and thyroid diseases and consists of Moschus, Ursi Fel, Bovis Calclus, Scutellaria baicalensis, Phellodendron amurense, Pulsatilla koreana, Sophorae Tonkinensis Radix et Rhizoma, Aucklandia lappa, and Hominis Placenta..
6. Distribution of treatment methods
A total of 341 patients (99.71%) received acupuncture, 251 (73.39%) were prescribed herbal medicine, 340 (99.42%) received pharmacopuncture, 298 (87.13%) received KM physiotherapy, and 153 (44.74%) received chuna therapy. Among patients receiving pharmacopuncture medicine, 126 (36.84%), 109 (31.87%), and 105 (30.70%) received one, two, or three or more types of pharmacopuncture. Regarding the types of pharmacopuncture used, when including duplicated pharmacopuncture, there were 180 (52.63%) cases of TA named after traffic accidents (Scutellaria baicalensis, Phellodendron amurense, Pulsatilla koreana, Sophorae Tonkinensis Radix et Rhizoma, Aucklandia lappa, and Carthamus tinctorius L.), 119 (34.80%) cases of HO named after Honghwaja (Carthamus tinctorius L), 87 (25.44%) cases of CH named after channel and developed to control pain using sodium channels by adding salt (Moschus, Ursi Fel, Bovis Calclus, Scutellaria baicalensis, Phellodendron amurense, Pulsatilla koreana, Sophorae Tonkinensis Radix et Rhizoma, Aucklandia lappa, and salt), 85 (24.85%) cases of MOK commonly used to treat clinical symptoms related to heart and thyroid diseases (Moschus, Ursi Fel, Bovis Calclus, Scutellaria baicalensis, Phellodendron amurense, Pulsatilla koreana, Sophorae Tonkinensis Radix et Rhizoma, Aucklandia lappa, and Hominis Placenta), and 46 other pharmacopuncture cases (13.45%) (Table 3). Pharmacopuncture used was manufactured at Namsangcheon extramural herbal medicine Dispensary (Yongin, Korea).
7. Treatment duration and number of treatments, NRS before and after treatment, and symptom improvement for each characteristic
1) Overall resultsThe mean treatment duration and number of treatments for all patients were 37.68 ± 45.11 days and 11.68 ± 10.63 treatments, respectively. The initial NRS was 7.32 ± 0.96 and decreased to 3.57 ± 1.40 at the end of treatment, with a symptom improvement score of 1.87 ± 0.60 (Table 4).
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Table 4 . Treatment duration, number of treatments, NRS, and improvement score according to demographic characteristics.
Treatment
durationNumber of treatments Initial NRS Posttreatment NRS Symptom improvement Sex Male (n = 209) 32.90 ± 35.09 10.62 ± 9.05 7.27 ± 0.94 3.53 ± 1.45 1.84 ± 0.63 Female (n = 138) 45.18 ± 56.92 13.35 ± 12.62 7.39 ± 0.98 3.64 ± 1.30 1.91 ± 0.55 p-value 0.000** 0.008** 0.740 0.173 0.032* Age (years) < 30 (n = 72) 42.92 ± 60.84 11.43 ± 11.92 7.31 ± 0.97 3.49 ± 1.45 1.81 ± 0.54 30 ≤, <40 (n = 137) 29.85 ± 34.29 9.78 ± 9.14 7.25 ± 0.93 3.84 ± 1.43 1.95 ± 0.61 40 ≤, <50 (n = 79) 37.67 ± 38.87 11.99 ± 9.08 7.37 ± 1.04 3.34 ± 1.25 1.84 ± 0.64 50 ≤, <60 (n = 36) 50.25 ± 47.59 16.83 ± 14.28 7.44 ± 0.80 3.21 ± 1.18 1.72 ± 0.56 60 ≤ (n = 18) 51.11 ± 57.85 15.44 ± 10.65 7.42 ± 0.89 3.61 ± 1.46 1.94 ± 0.62 p-value 0.001** 0.004** 0.798 0.333 0.823 All (n = 342) 37.68 ± 45.11 11.68 ± 10.63 7.32 ± 0.96 3.57 ± 1.40 1.87 ± 0.61 Values are mean ± SD. Statistical analyses were performed using independent two-sample t–tests or analysis of variance (ANOVA). *p < 0.05 and **p < 0.01..
NRS, numerical rating scale..
The mean treatment duration and number of treatments in men was 32.90 ± 35.09 days and 10.62 ± 9.05 treatments, respectively. The NRS decreased from 7.27 ± 0.94 to 3.53 ± 1.45, with an improvement score of 1.84 ± 0.63. In women, the mean treatment duration and number of treatments were 45.18 ± 56.92 days and 13.35 ± 12.62 treatments, respectively. The NRS decreased from 7.39 ± 0.98 to 3.64 ± 1.30, with an improvement score of 1.91 ± 0.55. Significant differences were observed in treatment duration (p < 0.01) and number of treatments (p < 0.01).
The mean treatment duration and number of treatments in patients less than 30 years of age was 42.92 ± 60.84 days and 11.43 ± 11.92 treatments, respectively. The NRS decreased from 7.31 ± 0.97 to 3.49 ± 1.45, with an improvement score of 1.81 ± 0.54. Among patients in their 30s, the mean treatment duration and number of treatments were 29.85 ± 34.29 days and 9.78 ± 9.14 treatments, respectively. The NRS decreased from 7.25 ± 0.93 to 3.84 ± 1.43, with an improvement score of 1.95 ± 0.61. Among patients in their 40s, the mean treatment duration and number of treatments were 37.67 ± 38.87 days and 11.99 ± 9.08 treatments, respectively. The NRS decreased from 7.37 ± 1.04 to 3.34 ± 1.25, with an improvement score of 1.84 ± 0.64. Among patients in their 50s, the mean treatment duration and number of treatments were 50.25 ± 47.59 days and 16.83 ± 14.28, respectively. The NRS decreased from 7.44 ± 0.80 to 3.21 ± 1.18, with an improvement score of 1.72 ± 0.56. Among patients in their 60s and older, the mean treatment duration and number of treatments were 51.11 ± 57.85 days, and 15.44 ± 10.65 treatments, respectively. The NRS decreased from 7.42 ± 0.89 to 3.61 ± 1.46, with an improvement score of 1.94 ± 0.62. Significant differences were observed in treatment duration (p < 0.01) and number of treatments (p < 0.01) according to patient age (Table 4).
3) Treatment results according to disease durationThe mean treatment duration and number of treatments during the most acute phase (within 1 week) was 33.49 ± 40.23 days and 11.58 ± 11.01 treatments, respectively. The NRS decreased from 7.30 ± 0.94 to 3.52 ± 1.41, with an improvement score of 1.86 ± 0.60. In the acute phase (within 1 week-1 month), the mean treatment duration and number of treatments were 41.89 ± 46.72 days and 11.00 ± 8.99 treatments, respectively. The NRS decreased from 7.37 ± 1.02 to 3.78 ± 1.37, with an improvement score of 1.94 ± 0.64. In the subacute stages (1-6 months after onset), the mean treatment duration and number of treatments were 84.79 ± 80.44 days and 17.43 ± 12.62, respectively. The NRS decreased from 7.39 ± 0.81 to 3.43 ± 1.10, with an improvement score of 1.71 ± 0.45. Significant differences in mean treatment duration (p < 0.01) and number of treatments (p < 0.01) were observed according to the disease duration but not for NRS change and the improvement score (Table 5).
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Table 5 . Treatment duration, number of treatments, NRS, and improvement score according to disease duration and traffic accident characteristics.
Treatment duration Number of treatments Initial NRS Posttreatment NRS Symptom improvement Mean ± SD Disease duration Within 1 week (n = 242) 33.49 ± 40.23 11.58 ± 11.01 7.30 ± 0.94 3.51 ± 1.41 1.86 ± 0.60 Acute stage (n = 87) 41.89 ± 46.72 11.00 ± 8.99 7.37 ± 1.02 3.78 ± 1.37 1.94 ± 0.64 Subacute stage (n = 13) 84.79 ± 80.44 17.43 ± 12.62 7.39 ± 0.81 3.43 ± 1.10 1.71 ± 0.45 p-value 0.001** 0.004** 0.902 0.957 0.852 Traffic accident situation Traffic accident patterns Rear impact (n = 218) 35.73 ± 38.40 11.73 ± 10.54 7.28 ± 0.97 3.52 ± 1.32 1.85 ± 0.57 Frontal impact (n = 14) 29.50 ± 29.81 10.21 ± 6.90 7.25 ± 0.87 3.5 ± 1.41 1.86 ± 0.83 Side impact (n = 36) 26.31 ± 22.84 8.08 ± 5.51 7.38 ± 0.85 3.64 ± 1.52 1.86 ± 0.63 Multiple impact (n = 18) 25.83 ± 24.46 8.11 ± 5.87 7.56 ± 0.90 4.47 ± 1.65 2.11 ± 0.57 Pedestrian (n = 23) 97.57 ± 94.88 21.61 ± 16.55 7.63 ± 0.85 3.24 ± 1.20 1.70 ± 0.55 Motorbike, bicycle, others (n = 27) 25.85 ± 25.97 9.63 ± 6.67 7.06 ± 0.95 3.69 ± 1.5 1.96 ± 0.69 On the bus (n = 6) 55.17 ± 68.40 17.00 ± 19.03 7.33 ± 1.18 3.5 ± 1.04 2 ± 0.58 p-value 0.070 0.347 0.296 0.276 0.665 Location Driver (n = 257) 34.26 ± 35.77 11.25 ± 9.92 7.33 ± 0.95 3.61 ± 1.42 1.89 ± 0.61 Passenger (n = 17) 23.65 ± 14.12 7.35 ± 4.90 7.50 ± 0.87 3.71 ± 1.48 1.82 ± 0.53 Back (n = 12) 25.00 ± 31.80 7.92 ± 5.71 7.04 ± 1.12 3.38 ± 0.88 1.67 ± 0.49 Pedestrian (n = 23) 97.57 ± 94.88 21.61 ± 16.55 7.63 ± 0.85 3.24 ± 1.20 1.70 ± 0.55 Motorbike, bicycle, others (n = 27) 25.85 ± 25.97 9.63 ± 6.67 7.06 ± 0.95 3.69 ± 1.5 1.96 ± 0.69 Bus (n = 6) 55.17 ± 68.40 17.00 ± 19.03 7.33 ± 1.18 3.5 ± 1.04 2 ± 0.58 p-value 0.004** 0.034* 0.238 0.843 0.542 Values are mean ± SD. Statistical analyses were performed using analysis of variance (ANOVA). *p < 0.05 and **p < 0.01..
NRS, numerical rating scale..
Among the accident types, the mean treatment duration and number of treatments in rear collision were 35.73 ± 38.40 days and 11.73 ± 10.54 treatments, respectively. The NRS decreased from 7.28 ± 0.97 to 3.52 ± 1.32, with an improvement score of 1.85 ± 0.57. For forward collisions, the mean treatment duration and number of treatments were 29.50 ± 29.81 days and 10.21 ± 6.90 treatments, respectively. The NRS decreased from 7.25 ± 0.87 to 3.5 ± 1.41, with an improvement score of 1.86 ± 0.83. For lateral collision, the mean treatment duration and number of treatments were 26.31 ± 22.84 days and 8.08 ± 5.51, respectively. The NRS decreased from 7.38 ± 0.85 to 3.64 ± 1.52, with an improvement score of 1.86 ± 0.63. For multi-collision, the mean treatment duration and number of treatments were 97.57 ± 94.88 days and 21.61 ± 16.55 treatments, respectively. The NRS decreased from 7.56 ± 0.90 to 4.47 ± 1.65, with an improvement score of 2.11 ± 0.57. For pedestrian accidents, the mean treatment duration and number of treatments were 33.49 ± 40.23 days and 11.58 ± 11.01, respectively. The NRS decreased from 7.63 ± 0.85 to 3.24 ± 1.20, with an improvement score of 1.70 ± 0.55. For vehicle and motorcycle accidents, the mean treatment duration and number of treatments were 25.85 ± 25.97 days and 9.63 ± 6.67 treatments, respectively. The NRS decreased from 7.06 ± 0.95 to 3.69 ± 1.53, with an improvement score of 1.96 ± 0.69. For bus passengers, the mean treatment duration and number of treatments were 55.17 ± 68.40 days, and 17.00 ± 19.03, respectively. The NRS decreased from 7.33 ± 1.18 to 3.5 ± 1.04, with an improvement score of 2 ± 0.58. No significant differences were observed in treatment duration, number of treatments, NRS before and after treatment, or improvement according to the accident type.
Among locations at the time of the accident, the mean treatment duration and number of treatments were 34.26 ± 35.77 days and 11.25 ± 9.92 treatments, respectively, for the driver seat. The NRS decreased from 7.33 ± 0.95 to 3.61 ± 1.42, with an improvement score of 1.89 ± 0.61. For the passenger seat, the mean treatment duration and number of treatments were 23.65 ± 14.12 days and 7.35 ± 4.90 treatments, respectively. The NRS decreased from 7.50 ± 0.87 to 3.71 ± 1.48, with an improvement score of 1.82 ± 0.53. For the rear seat, the mean treatment duration and number of treatments were 25.00 ± 31.80 days and 7.92 ± 5.71, respectively. The NRS decreased from 7.04 ± 1.12 to 3.38 ± 0.88, with an improvement score of 1.67 ± 0.49. Significant differences were observed in treatment duration (p < 0.01) and number of treatments (p < 0.01) according to the location at the time of the accident, but not for NRS before and after treatment or improvement score (Table 5).
5) Treatment results according to the presence of symptoms other than pain and psychological symptomsIn the presence of additional symptoms, the mean treatment duration and number of treatments were 40.24 ± 48.57 days and 12.51 ± 11.62, respectively. The NRS decreased from 7.34 ± 1.01 to 3.53 ± 1.36, with an improvement score of 1.87 ± 0.61. In the absence of additional symptoms, the mean treatment duration and number of treatments were 29.69 ± 31.30 days and 9.07 ± 6.13, respectively. The NRS decreased from 7.24 ± 0.75 to 3.72 ± 1.50, with an improvement score of 1.95 ± 0.66. Significant differences were observed for treatment duration (p < 0.05), number of treatments (p < 0.05), and pre (p < 0.01) and post-treatment NRS (p < 0.05).
The average treatment duration and number of treatments in patients with psychological symptoms, were 44.74 ± 58.72 days and 14.28 ± 14.74 treatments, respectively. The NRS decreased from 7.34 ± 1.01 to 3.53 ± 1.36, with an improvement score of. 1.87 ± 0.61. In the absence of psychological symptoms, the mean treatment duration and number of treatments were 35.72 ± 40.58 days and 10.96 ± 9.11 treatments, respectively. The initial NRS decreased from 7.24 ± 0.75 to 3.72 ± 1.50, with an improvement score of 1.95 ± 0.66. Significant differences in treatment duration (p < 0.05) and number of treatments (p < 0.01) were observed according to the presence of psychological symptoms but not for NRS and improvement score (Table 6).
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Table 6 . Treatment duration and number, NRS, and improvement according to additional symptoms, psychological symptoms, and chuna.
Treatment
durationNumber of treatments Initial NRS Posttreatment NRS Symptom improvement Mean ± SD Additional symptoms Yes (n = 259) 40.24 ± 48.57 12.51 ± 11.62 7.34 ± 1.01 3.53 ± 1.36 1.87 ± 0.61 No (n = 83) 29.69 ± 31.30 9.07 ± 6.13 7.24 ± 0.75 3.72 ± 1.50 1.95 ± 0.66 p-value 0.017* 0.010* 0.001** 0.038* 0.476 Psychological symptoms Yes (n = 74) 44.74 ± 58.72 14.28 ± 14.74 7.34 ± 0.94 3.54 ± 1.41 1.86 ± 0.56 No (n = 268) 35.72 ± 40.58 10.96 ± 9.11 7.31 ± 0.96 3.58 ± 1.40 1.87 ± 0.62 p-value 0.006** 0.017* 0.897 0.774 0.589 Chuna Yes (n = 153) 54.58 ± 50.25 17.84 ± 11.80 7.67 ± 0.91 3.21 ± 1.10 1.71 ± 0.55 No (n = 185) 23.25 ± 34.62 6.38 ± 5.52 7.01 ± 0.89 3.89 ± 1.54 2.01 ± 0.62 p-value 0.000** 0.005** 0.767 0.000** 0.023* Values are mean ± SD. Statistical analyses were performed using the independent two-sample t–tests. *p < 0.05 and **p < 0.01..
NRS, numerical rating scale..
The mean duration and number of chuna treatments were 54.58 ± 50.25 days and 17.84 ± 11.80, respectively. The NRS decreased from 7.67 ± 0.91 to 3.21 ± 1.10, with an improvement score of 1.71 ± 0.55. In cases without chuna treatment, the mean treatment duration and number of treatments were 23.25 ± 34.62 days and 6.38 ± 5.52, respectively. The NRS decreased from 7.01 ± 0.89 to 3.89 ± 1.54, with an improvement score of 2.01 ± 0.62. No significant difference in NRS was observed before treatment; however, significant differences were observed in treatment duration (p < 0.01), number of treatments (p < 0.01), post-treatment NRS (p < 0.01), and improvement score (p < 0.05) (Table 6).
7) Treatment results according to the treatment number and durationAnalysis of the number of treatments showed an NRS decrease from 7.01 ± 0.90 to 3.91 ± 1.55 and an improvement score of 2.02 ± 0.63 for 10 or fewer treatments. For 20 or fewer treatments, the NRS decreased from 7.7 ± 0.84 to 3.13 ± 0.93, with an improvement score of 1.72 ± 0.45. For 30 or fewer treatments, the NRS decreased from 7.83 ± 0.81 to 2.89 ± 0.93, with an improvement score of 1.44 ± 0.50. Finally, for more than 30 treatments, the NRS decreased from 8.02 ± 0.85 to 3.10 ± 0.92, with an improvement score of 1.57 ± 0.49. Significant differences were observed in initial NRS (p < 0.01), and improvement score (p < 0.05).
Analysis of the treatment period showed that NRS decreased from 7.07 ± 0.90 to 3.81 ± 1.53, with an improvement score of 1.96 ± 0.64 within one month. Within 2 months, the NRS decreased from 7.59 ± 0.85 to 3.12 ± 1.06, with an improvement score of 1.76 ± 0.52. Within 3 months, the NRS decreased from 8 ± 0.80 to 3.43 ± 1.00, with an improvement score of 1.76 ± 0.43. Within 4 months, the NRS decreased from 8.05 ± 0.93 to 2.7 ± 0.6, with an improvement score of 1.3 ± 0.46. Finally, for more than 4 months, the NRS decreased from 7.81 ± 0.99 to 3.11 ± 0.72, with an improvement score of 1.67 ± 0.47. Significant difference in NRS was observed before treatment (p < 0.01); however, no significant differences were observed in post-treatment NRS and improvement score (Table 7).
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Table 7 . NRS, and improvement score according to treatment duration and number of treatments.
Initial NRS Posttreatment NRS Symptom improvement Mean ± SD Number of treatment ≤ 10 (n = 204) 7.01 ± 0.90 3.91 ± 1.55 2.02 ± 0.63 ≤ 20 (n = 90) 7.7 ± 0.84 3.13 ± 0.93 1.72 ± 0.45 ≤ 30 (n = 27) 7.83 ± 0.81 2.89 ± 0.93 1.44 ± 0.50 > 30 (n = 21) 8.02 ± 0.85 3.10 ± 0.92 1.57 ± 0.49 p-value 0.002** 0.952 0.041* Period of treatment ≤ 1 month (n = 205) ≤ 1 week (n = 40) 7.07 ± 0.90 6.96 ± 0.90 3.81 ± 1.53 4.96 ± 1.35 1.96 ± 0.64 2.35 ± 0.61 ≤ 2 week (n = 57) 6.86 ± 0.98 3.94 ± 1.52 2.06 ± 0.65 ≤ 3 week (n = 44) 7.16 ± 0.90 3.26 ± 1.35 1.75 ± 0.53 ≤ 1 month (n = 64) 7.30 ± 0.74 3.32 ± 1.32 1.75 ± 0.5 ≤ 2 month (n = 67) 7.59 ± 0.85 3.12 ± 1.06 1.76 ± 0.5 ≤ 3 month (n = 29) 8 ± 0.80 3.43 ± 1.00 1.76 ± 0.43 ≤ 4 month (n = 10) 8.05 ± 0.93 2.7 ± 0.6 1.3 ± 0.46 ≥ 4 month (n = 18) 7.81 ± 0.99 3.11 ± 0.72 1.67 ± 0.47 p-value 0.002** 0.131 0.212 Values are mean ± SD. Statistical analyses were performed using analysis of variance (ANOVA). *p < 0.05 and **p < 0.01..
NRS, numerical rating scale..
The treatment number and duration were significantly positively correlated with initial NRS (both p < 0.001) and significantly negatively correlated with post-treatment NRS (p < 0.001, p < 0.001) and improvement score (both p < 0.001). The higher the number of treatments and the longer the treatment duration, the higher the initial NRS, lower the post-treatment NRS, and the better the improvement score (Table 8).
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Table 8 . Correlation analysis between treatment period and number, NRS, and improvement.
Number of treatments Treatment period Initial NRS Post-treatment NRS Symptom improvement r (p) Number of treatments 1 0.815** (0.000) 0.304** (0.000) –0.205** (0.000) –0.216** (0.000) Treatment period 1 0.353** (0.000) –0.290** (0.000) –0.308** (0.000) Initial NRS 1 0.154** (0.004) –0.140** (0.010) Posttreatment NRS 1 0.764** (0.000) Symptom improvement 1 Statistical significance was evaluated by Pearson’s correlation analysis..
r: correlation. p: p-value. **p < 0.01..
NRS, numerical rating scale..
A total of 340 patients received pharmacopuncture. In December 2017, TA pharmacopuncture was developed to treat traffic accident patients. We investigated the use of pharmacopuncture. Before the introduction of TA pharmacopuncture, 10 (7.81%), 49 (38.28%), and 69 cases (53.91%) received one, two, or three or more types of acupuncture, respectively. After the introduction of TA pharmacopuncture, 116 (54.72%), 60 (28.30%), and 36 (16.98%) cases received one, two, or three or more types of acupuncture, respectively. Since the introduction of TA pharmacopuncture, the rate of use of one type of pharmacopuncture increased from 7.81% to 54.72%. Before using TA pharmacopuncture, the mean treatment duration and number of treatments were 38.17 ± 50.62 days and 11.15 ± 10.39, respectively; the NRS decreased from 7.32 ± 0.97 to 3.54 ± 1.42, with and an improvement score of 1.85 ± 0.63. After the introduction of TA pharmacopuncture, the treatment duration and number of treatments were 37.48 ± 41.87 days and 12.01 ± 10.85, respectively; the NRS decreased from 7.32 ± 0.95 to 3.59 ± 1.3, with an improvement score of 1.88 ± 0.56. No significant differences were observed between treatment groups before and after TA pharmacopuncture in treatment duration and number, NRS before and after treatment, and improvement score (Table 9).
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Table 9 . Use of main pharmacopuncture methods.
Total number of pharmacopuncture types
used for treatmentTreatment period (days) Number of treatments Initial NRS Post-treatment NRS Symptom
improvementMean ± SD Using TA Before (n = 128) 1 (n = 10) 39.70 ± 45.60 7.50 ± 6.62 7.15 ± 0.85 3.90 ± 1.76 2.00 ± 0.82 2 (n = 49) 40.43 ± 59.38 12.06 ± 12.83 7.41 ± 0.98 3.67 ± 1.54 1.90 ± 0.65 3 or more (n = 69) 36.35 ± 44.87 10.97 ± 8.81 7.22 ± 0.97 3.38 ± 1.28 1.81 ± 0.60 38.17 ± 50.62 11.15 ± 10.39 7.32 ± 0.97 3.54 ± 1.42 1.85 ± 0.63 After (n = 212) 1 (n = 116) 26.26 ± 29.46 8.46 ± 7.14 7.12 ± 0.92 3.79 ± 1.43 1.99 ± 1.67 2 (n = 60) 45.05 ± 54.71 14.10 ± 12.51 7.51 ± 1.01 3.14 ± 1.24 1.67 ± 0.51 3 or more (n = 36) 61.03 ± 39.85 20.08 ± 12.66 7.74 ± 0.78 3.68 ± 1.35 1.83 ± 0.51 37.48 ± 41.87 12.01 ± 10.85 7.32 ± 0.95 3.59 ± 1.39 1.88 ± 0.56 p-value 0.325 0.331 0.524 0.843 0.337 Total (n = 340) 37.74 ± 45.29 11.69 ± 10.67 7.32 ± 0.96 3.57 ± 1.40 1.87 ± 0.61 Values are mean ± SD. Statistical analyses were performed using independent two-sample t–tests. *p < 0.05 and **p < 0.01..
TA: a pharmacopuncture extract named for traffic accidents consisting of Scutellaria baicalensis, Phellodendron amurense, Pulsatilla koreana, Sophora tonkinensis, Aucklandia lappa, Aquilaria agallocha, and Carthamus tinctorius L..
NRS, numerical rating scale..
No adverse reactions including infection, bleeding, hematoma, fatigue, sweating, severe nausea, dizziness, and headache, were observed for any treatment. Sixteen cases of pain, 16 cases of body ache, 10 cases of tingling feelings, and one case of tingling skin were reported during treatment. The treatment rejections included three pharmacopuncture treatment rejections, one CP pharmacopuncture medicine rejection, one electro-acupuncture treatment rejection, and one rejection for all kinds of needle treatment.
DISCUSSION
Traffic accidents are a social problem that poses a serious threat to people’s lives, causing pain and mental anguish for the victims and their families. Furthermore, the number of traffic accident patients and medical expenses are rising due to increased automobile use. The number of patients visiting KM institutions is constantly increasing due to KM automobile insurance coverage and patient satisfaction for the treatment of traffic accidents; moreover, to compensate for the lack of treatment in WM institutions, traffic accident patients often chose KM treatment such as acupuncture, herbal medicine, chuna, and pharmacopuncture, and they experience satisfaction after treatment and showed self-diffusion and ambient diffusion for KM treatment [8, 12]. Various domestic and international clinical and experimental studies have assessed the effects of KM treatment for treating traffic accident injury syndrome, and more patients are expected to use KM treatment in the future [12, 13]. However, there are few reports related to automobile insurance care at KM clinics, which was ranked first among medical billing by type of medical institution [9]; thus, there is a need to determine the medical status at KM Clinics. Therefore, this study investigated the medical status of 342 traffic accident patients who visited the Jisung Kyunghee KM clinic between January 1, 2017, and June 30, 2019.
Of the 342 patients, 209 (61.11%) were men and 138 (38.99%) were women, with men 1.51 times more predominant than women. This finding differed from those of previous reports of more female patients in car accidents in Korea [7, 8]. One explanation for this difference may be the many opportunities for treatment of male patients in the present study because our clinic is located in a city with many floating populations. In terms of age distribution, patients in their 30s and 40s accounted for about 63% of the patient population and patients in their 20s-50s accounted for about 95% of the total. This finding is concordant with that of previous reports suggesting the greatest risk of traffic accidents in the age groups which is the main cause of social activity [11], in which there are not only many drivers in the younger age groups but also concern regarding the aftermath of traffic accidents. No significant differences in NRS before and after treatment or improvement score was observed according to sex and age, but a statistically significant difference was observed for treatment duration and number of treatments. The significantly higher treatment period and number of treatments in women compared to those in men may be linked to the results of previous studies reporting that women have a lower employment rate than men, have more time for treatment, and are more susceptible to trauma and the aftereffects of traffic accidents [14, 15].
The treatment period and number of treatments were lowest in patients in their 30s and were lower for patients in their 20s and 40s than for those in their 50s or older. This finding may be related to previous reports that young people are relatively active in seeking treatment because of their high level of awareness and concern about the aftereffects of car accidents, with high treatment effects in the younger individuals, while middle-aged people in their 50s and 60s and elderly people in their 80s are less resilient to the aftereffects of car accidents [16].
Previous studies on traffic accident types observed many minor injuries due to being in the driver seat and rear collision among patients receiving KM treatment [7, 8]. In the present study, rear collisions (218, 63.74%) and driver seats (257, 75.15%) were also the most common factors. There were no statistically significant differences in treatment duration and number, NRS before and after treatment, improvement score according to accident type or in NRS before and after treatment, and improvement score according to the location at the time of the accident. In terms of the treatment period and number of treatments according to the location at the time of the accident, the treatment period was significantly longer and the number of treatments were higher in the order of pedestrian, bus passenger, driver seat, motorcycle or bicycle, back seat, and passenger seat, likely because a pedestrian experienced the greatest impact of a direct collision.
The main disease codes of traffic accident patients visiting KM institutions were sprains and strains of the c-spine (S13, 56.3%), sprains and strains of the lumbar and pelvic region (S33, 25.7%), and intracranial injury (S06, 8.0%) [3, 16, 17] accompanied by localized pain in various areas and systemic and mental symptoms [6, 9, 18-20]. The present study also observed various systemic and psychological symptoms, and all patients had localized pain. Meanwhile, pain around the lumbar and pelvic region and cervical spine and shoulders were observed in that order. For most cases with combined neck and shoulder muscle soreness, our clinic used code S43.4 (sprain and strain of the shoulder joint); therefore, the main disease code differed slightly from that in the previous report. In cases with additional symptoms and mental symptoms other than pain, the treatment duration and number were significantly longer; moreover, the NRS before treatment was larger in patients with additional symptoms. Therefore, the presence of symptoms other than pain may predict treatment duration and frequency.
Previous studies reported that most accidents on roads are minor [21]. Most patients who visit KM institutions are diagnosed with simple sprains owing to the characteristics of KM treatment that the primary care in WM hospitals excludes serious damage because that the more severe the pain after a traffic accident, the more often the first visit to WM hospital is chose [6, 8]. In our study, 134 patients (39.18%) visited our clinic first following a traffic accident, a finding likely to be the result of simple sprain in patients with minor accidents based on previous reports. Before coming to our clinic, 106 patients (30.99%) had been treated and tested at WM institutions and 52 (15.20%) were only tested at WM institutions, a finding consistent with those of a survey on KM use and herbal medicine consumption in 2017, in which 50.4% of KM outpatients first presented to other medical institutions, mainly WM clinics (55.4%), for treatment of the same symptoms. In previous studies, most traffic accident patients who visited KM institutions first presented to WM hospitals, which was attributed to psychological factors of the victims and perpetrators who preferred WM examination even though their symptoms were minor [6, 9]. The perspectives of these previous studies can be applied in the present study.
Regarding the motivation for selecting our clinic, 197 patients (57.60%) visited through an internet search, 70 were existing patients (20.47%), 36 (10.53%) visited due to acquaintance introduction, 35 (10.23%) visited due to proximity, and four (1.17%) patients selected our clinic for other reasons. A survey on KM use and herbal medicine consumption in 2017 reported that 34.9% of Koreans reported being aware of KM care and that information or knowledge on KM care were most commonly obtained from neighbors such as family and friends (38.6%), followed by broadcasting media (27.3%) and KM institutions (24.9%) [22]. Internet searches were likely the main motive for visiting our clinic because the market for KM automobile insurance has grown recently, and patients reportedly have high awareness and satisfaction with KM automobile insurance care [8]. Moreover, KM institutions are actively promoting and providing information, including in networks related to traffic accidents.
Regarding the duration of disease before presenting to our clinic, most patients (242, 70.76%) reported during the acute phase (within 1 week), and patients with acute and subacute phases had passed through other medical institutions during the most acute phase. Most patients likely visited medical institutions during the most acute phase because both the victim and offender felt the need for prompt treatment due to mental shock and discomfort in daily life immediately after the accident, in addition to psychological factors associated with compensation issues with auto insurance companies. No significant difference in NRS before and after treatment and improvement score according to the duration of disease were observed; however, a longer disease duration was associated with a longer treatment duration and higher number of treatments. Prospective studies have reported that most recoveries occur up to 3 months after the initial injury [23, 24]; thus, appropriate care management is important in the acute and subacute stages to prevent the development of chronic diseases [18]. To prevent the disease from becoming chronic, treatment should be started soon after the traffic accident.
Assessment of the distribution of treatment period showed that the majority of patients (218, 63.74%) completed treatment within 1 month, a finding concordant with those of previous reports from KM institutions that treatment rarely lasts for more than 1 month [9]. The average number of treatments was 11.68 ± 10.63; 204 (59.65%) and 90 (16.67%) patients received fewer than 10 and 20 treatments, respectively. This is consistent with a report indicating an average of 11.6 outpatient visits to KM in the past year in a survey of KM use and herbal medicine consumption in 2017 [22]. Furthermore, considering the treatment period, the number of treatments was not high because most patients could not attend daily due to social activities. The initial NRS of all patients, 7.32 ± 0.96, decreased to 3.57 ± 1.40 at the end of treatment; the improvement score, 1.87 ± 0.60, was between ① Excellent and ② Good. Analysis of the correlation between treatment duration and number, NRS change, and improvement score showed that the higher the number of treatments and the longer treatment duration, the higher the initial NRS, the lower the NRS after treatment, and the better the improvement score. This finding was related to that of a previous report demonstrating that the recovery rate was not constant in cases of prolonged treatment and depended on the degree of injury; furthermore, recovery was delayed due to social activities or labor during outpatient treatment [6]. Furthermore, this is thought to be an extension of the treatment period due to the severity of the treatment, rather than long-term treatment because the treatment effect is weak, given the NRS change and improvement scores.
Pharmacopuncture is a new acupuncture treatment combining acupuncture and herbal medicines that has been used for almost all types of diseases in KM clinical practice and is the second-most common treatment after acupuncture in traffic accident patients [8, 16]. In particular, HO, HN, V, OK, and TA are used to treat acute or chronic inflammation and pain in patients with musculoskeletal disorders and traffic accident injury syndrome [25-27]. In our clinic, 99.42% of patients were administered pharmacopuncture in the order of TA, HO, CH, and MOK, and various kinds of acupuncture were used alone or in combination during the treatment period. Chuna was performed when symptoms improved slowly or when additional treatment was needed; therefore, the number of patients treated with chuna (153 patients, 44.74%) was smaller than the number of patients receiving pharmacopuncture, and patients treated with chuna had significantly longer treatment periods and higher numbers of treatments.
In our study, TA was the most commonly used pharmacopuncture. The plant-based extract TA was developed in 2015 to replace the animal-based extracts Bovis Calculus-Ursi Fel- Moschus (BUM or V), for which it was difficult to obtain stable supplies. TN consists of Scutellariae Radix, Phellodendri Cortex, Pulsatillae Radix, Sophorae Tonkinensis Radix et Rhizoma, Aucklandiae Radix, Aquilariae Lignum, and Carthami Fructus and was named for its principal use in treating traffic accident-related injuries. TA has been experimentally confirmed to be safe; however, while its clinical use is increasing, there few clinical reports [26-28]. We started using TA pharmacopuncture in December 2017 and changed to a treatment method mainly using TA pharmacopuncture. Since TA acupuncture alone was used in more than 50% of cases, the variety of types of pharmacopuncture was less than that before TA pharmacopuncture. No statistically significant differences were observed in treatment duration and number, NRS before and after treatment, and improvement scores before and after TA pharmacopuncture, a finding that indicates the validity of the development of TA pharmacopuncture for the management of various symptoms caused by traffic accidents, with similar therapeutic effects in place of the role of various pharmacopuncture. However, additional large-scale TA pharmacopuncture-related clinical studies in traffic accident patients are warranted and, after excluding other treatments, group comparisons of the treatment effect and detailed analysis of this effect according to the pain area and symptoms should be performed.
The results of this study confirmed the high treatment effect of KM treatment under automobile insurance reported previously [6-9]. Significant correlations were also observed based on detailed medical status, which may be used as evidence to justify increased KM care in the auto insurance system. No specific adverse reactions were observed for any of the treatments, as well as no discomfort with sequelae; therefore, the safety of KM treatment for traffic accident patients was confirmed to some extent. This study was limited in that it was conducted at a single KM clinic, treatment satisfaction was not investigated, and the operator and evaluator were not blinded. In addition, due to the characteristics of general KM treatment, in which various treatment methods including acupuncture, pharmacopuncture, herbal medicine, physiotherapy, and chuna treatment are combined, the effects of each treatment method were not assessed. In order to accumulate more evidence on the therapeutic effect of oriental medicine on traffic accident injuries, it will be necessary to verify the effect of each KM treatment method and to compare the treatment effect between various KM treatment methods, and additional studies in other regions and larger, multicenter studies are needed.
CONCLUSION
This study confirmed the previous findings of a high treatment effect of KM under automobile insurance. We also observed significant correlations based on a detailed medical status, which may explain the increasing use of KM in the automobile insurance system. Additional studies in different regions and with larger and multi-center studies are needed.
CONFLICTS OF INTEREST
The authors declare that they have no conflicts of interest.
DATA AVAILABILITY
The data used to support the findings of this study are available from the corresponding author upon request.
AUTHORS’ CONTRIBUTIONS
JHH performed the data analysis and interpretation of the data. JHJ and JHH contributed to the study concept and design. JHJ conducted the study and data collection. JHH and JK performed the data analysis and interpretation of the data. JHH performed manuscript writing, and JHH and JHJ revised manuscript.
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Original Article
J Pharmacopuncture 2021; 24(3): 122-137
Published online September 30, 2021 https://doi.org/10.3831/KPI.2021.24.3.122
Copyright © The Korean Pharmacopuncture Institute.
A Single-Center Retrospective Study on the Effects of Korean Medicine in 342 Traffic Accident Cases
Jin-Ho Jeong1 , Jaseung Ku2
, Ji Hye Hwang3*
1Jisung-Kyunghee Korean Medicine Clinic, Seoul, Republic of Korea
2Bogwang Korean Medical Clinic, Seoul, Republic of Korea
3Department of Acupuncture & Moxibustion Medicine, College of Korean Medicine, Gachon University, Seongnam, Republic of Korea
Correspondence to:Ji Hye Hwang
Department of Acupuncture & Moxibustion Medicine, College of Korean Medicine, Gachon University, Seongnam 13120, Republic of Korea
Tel: +82-32-770-1342
E-mail: jhbori@nate.com
This is an Open-Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Objectives: In South Korea, traffic accident victims can be treated under automobile insurance coverage. Korean medicine (KM) clinics have reported the largest number of automobile insurance fee claims among medical institutions. This study investigated the status of the KM automobile insurance system in a single KM clinic.
Methods: We retrospectively surveyed the medical charts of 342 traffic accident patients treated at the Jisung KM clinic between January 2009 and June 2017.
Results: Most of the patients were men and in their 30s. The most common method of locating the clinic was an internet search. The most common traffic accident type was collision between vehicles (83.63%), with 70.76% of patients visiting during the most acute phase. The major disease codes included S434, M4836, F072, S0600, and S3350. The most frequent treatment period was within 1 month of the accident, and most patients received 10 or fewer treatments. The mean treatment duration and number of treatments were 37.68 ± 45.11 days and 11.68 ± 10.63 treatments, respectively. The initial pain numerical rating scale (NRS), 7.32 ± 0.96, decreased to 3.57 ± 1.40 at the end of treatment, with a symptom improvement score of 1.87 ± 0.60. Regarding sex, age, disease duration, location at the time of the accident, presence of additional and psychological symptoms, and chuna, there were statistically significant differences in treatment duration and number of treatments. A higher number of treatments and the longer treatment duration was associated with a higher initial NRS, lower post-treatment NRS, and better improvement score. Since the introduction of traffic accident (TA) pharmacopuncture, the rate of use of a single type of pharmacopuncture increased; however, no significant differences in treatment duration and number, NRS before and after treatment, and improvement score were observed between treatment groups before and after TA pharmacopuncture. No adverse reactions were observed for any treatment.
Conclusion: This study confirmed the previous findings of a high treatment effect of KM under automobile insurance. We also observed significant correlations based on a detailed medical status, which may explain the increasing use of KM in the automobile insurance system. Additional multi-center studies in different regions are needed.
Keywords: automobile insurance, traffic accident, korean medicine, acupuncture, pharmacopuncture, retrospective study
INTRODUCTION
Traffic accident injuries are common and can cause unexpected pain and functional decline [1]. The estimated associated annual costs after road accidents in 2016 exceeded £35 billion in the United Kingdom and exceeded USD 21 billion in South Korea, accounting for approximately 1.4% of the gross domestic product [2, 3]. As traffic accidents cause serious socioeconomic problems worldwide, the management of injuries and aftereffects of traffic accidents has become an important issue.
In South Korea, traditional Korean medicine (TKM) techniques, such as acupuncture and herbal medicine, along with chuna manual therapy, pharmacopuncture, and physical therapy are now included in the automobile insurance coverage and are provided to traffic accident patients [4]. According to the Automobile Insurance Statistical Data from the Health Insurance Review & Assessment Service, TKM automobile insurance medical expenses doubled, from KRW 357.8 billion in 2015 to KRW 713.9 billion in 2018. In addition, a 21% increase in the number of patients at TKM institutions was reported, compared to a 1% increase at western medicine (WM) institutions [5].
Traffic accident patients have more mild injuries such as simple sprains and concussions than severe injuries, and most patients complain of neck and back pain [6]. Sprains of the cervical and lumbar spine show no major abnormalities in radiological assessments, and many patients prefer TKM for conservative treatment [7].
In 2018, medical expenses associated with TKM, including at 295 TKM hospitals and 11,582 TKM clinics, increased by 28.76% year-on-year to KRW 713.9 billion. In particular, TKM clinics accounted for the largest percentage of the 19,650 medical institutions providing automobile insurance and ranked first in the total number of claims and total care costs for automobile insurance [5].
Owing to the rapid growth of the TKM automobile insurance market, data on satisfaction and improvement following TKM treatment have been collected [6, 8]; however, there are few reports on the status of automobile insurance treatments at TKM clinics [9]. Therefore, additional reports on the medical status at TKM clinics are needed. Thus, this study retrospectively analyzed the current status and effect of automobile insurance TKM treatment in a single TKM clinic and verified the justification for TKM treatment under automobile insurance.
MATERIALS AND METHODS
1. Subjects
This study included 342 of 385 patients who received outpatient treatment at Jisung Kyunghee TKM Clinic for traffic accident injuries between January 1, 2017, and June 30, 2019, except for 43 patients who did not find accurate treatment results. The 43 excluded patients included 26 who received fewer than two treatments, two for whom improvement could not be confirmed in the chart records, two who were treated once in our clinic and in another clinic for several months, four who visited more than 6 months after the accident, eight under 19 years of age, and one who received only four treatments in preparation for pregnancy after abortion. This study was a retrospective review of the charts of patients who provided informed consent and was approved by the Institutional Review Board of Gachon University Korean Medical Hospital (IRB No. M-19-123).
2. Research method
The 342 cases were examined for overall medical treatment status according to sex and age, accident type, disease duration, symptoms and diagnosis, and treatment duration and frequency. We analyzed the treatment duration and frequency, pain numerical rating scale (NRS) before and after treatment, and symptom improvement score according to sex and age, accident type, disease duration, additional symptoms and psychological symptoms, and chuna treatment. We also analyzed the status of patients who received pharmacopuncture and investigated the treatment response and adverse events during the treatment period.
3. Evaluation of treatment grade and symptom improvement
The pain index used in this study was the NRS. The initial NRS was defined as the most severe pain immediately after the accident, while the late NRS was that at the end of treatment. Subjective symptom improvement was classified into four stages: (1) Excellent (no functional impairment due to normal recovery of subjective symptoms and physical examination), (2) good (subjective symptoms and physical examination showed clear improvement compared to those in the first visit), (3) fair (improvement or slight improvement on subjective symptoms and physical examination), and (4) poor (no improvement or worsened condition on subjective symptoms and physical examination) using Odom’s criteria [8-11] and a score of 1-4 points using a Likert four-point scale.
4. Intervention
Acupuncture was performed for 15 minutes with disposable stainless needles (0.25 mm in diameter and 40 mm in length, Dong Bang, Boryeong, Korea) at a depth of 10-30 mm, depending on the insertion site. The acupoints were mainly the GB20, GV17, GB21, GV4, GV3, BL23, GV30, and ouch points (ashi points). According to the patient’s symptoms, electro-acupuncture stimulation, cupping, pharmacopuncture, and chuna manual therapy were combined. In cases requiring drug treatment, concussion symptoms were first treated with a concussion prescription, which is a combination of Dohongsamultang and BanhabaekchulcheonMatang; in addition, Hwaeojeon-gami prescription was used for trauma blood stasis. Physiotherapy was performed once daily, mainly using interferential current therapy and a hot pack according to the patient’s condition.
5. Safety and adverse reactions to treatment
Immediately after each treatment and at the next visit, we checked for bleeding, hematoma, fatigue, sweating, severe nausea, dizziness, and headache, as well as infections and patient discomfort related to treatments such as acupuncture, pharmacopuncture, herbal medicine, and chuna treatment.
6. Statistical analysis
The statistical analyses were performed using IBM SPSS Statistics for Windows, version 25.0. Relationships between the treatment period and number, NRS before and after treatment, and symptom improvement for each factor were assessed by independent two-sample t-tests for two groups and one-way analysis of variance (ANOVA) for three or more groups. The correlations between the treatment duration, number of treatments, NRS before and after treatment, and improvement were evaluated by Pearson’s correlation analysis. p < 0.05 was considered statistically significant.
RESULTS
1. Distribution by sex, age, visit motivation, and disease duration
The study population was composed of 1.51 times more men (n = 209, 61.11%) than women (n = 138, 38.99%). The age distribution was as follows: individuals in their 20s (n = 72, 21.05%), 30s (n = 137, 40.06%), 40s (n = 79, 23.10%), 50s (n = 36, 10.53%), and 60s or older (n = 18, 5.26%). The most common motivations for visiting the clinic were an internet search (197 patients, 57.60%), followed by previous treatment at our clinic (70 patients, 20.47%), introduction by acquaintances (36 patients, 10.53%), proximity (35 patients, 10.23%), and other reasons (4 patients, 1.17%). Most patients (242, 70.76%) visited during the most acute phase (within 1 week); 87 patients (25.44%) visited in the acute phase (1 week-1 month) and 13 patients (3.80%) visited during the subacute stages (1-6 months after onset) (Table 1).
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TKM, traditional Korean medicine; WM, Western medicine..
&md=tbl&idx=1' data-target="#file-modal"">Table 1Patient characteristics.
Characteristics Sex Total
number (%)Male Female Age group (years) < 30 35 (10.23) 37 (10.82) 72 (21.05) 30 ≤, < 40 97 (28.36) 40 (11.70) 137 (40.06) 40 ≤, < 50 52 (15.20) 27 (7.89) 79 (23.10) 50 ≤, < 60 20 (5.85) 16 (4.68) 36 (10.53) 60 ≤ 5 (1.46) 13 (3.80) 18 (5.26) Motivation for visiting Web search 120 (35.09) 77 (22.51) 197 (57.60) Current patient 42 (12.28) 28 (8.19) 70 (20.47) Acquaintance introduction 22 (6.43) 14 (4.09) 36 (10.53) Close distance 23 (6.73) 12 (3.51) 35 (10.23) Other 2 (0.58) 2 (0.58) 4 (1.17) Duration between
accident and visiting
our clinicWithin 1 week Accident day 19 (5.56) 9 (2.63) 242 (70.76) 1-2 days 82 (23.98) 31 (9.06) 3-7 days 54 (15.79) 37 (10.82) 1 week-1 month (Acute stage) 46 (13.45) 41 (11.99) 87 (25.44) 2-6 months (Subacute stage) 8 (2.34) 5 (1.46) 13 (3.8) Patterns of visiting
our clinicVia other
medical institutionTKM Outpatient 2 (0.58) Radioactive examination & TKM outpatient 2 (0.58) TKM hospital inpatient with radioactive examination 11 (3.22) WM Radioactive examination 52 (15.20) Discharge after admission and treatment 35 (10.23) Radioactive examination & WM outpatient 106 (30.99) Direct visit 134 (39.18) TKM, traditional Korean medicine; WM, Western medicine..
2. Distribution of patterns of visiting our clinic
A total of 134 patients (39.18%) visited our clinic without visiting other hospitals, while 208 (60.82%) visited our clinic after visiting another hospital. Among patients who visited WM institutions, 52 (15.20%) received only physical and radiological examinations without treatment, 35 (10.23%) visited our clinic after inpatient treatment at WM hospitals, and 106 (30.99%) visited our clinic after examination and outpatient treatment at WM clinics. Among patients who visited KM institutions, 11 (3.22%) were hospitalized with radiological examinations and two (0.58% each) visited our clinic after visiting another KM clinic with or without radiological examination (Table 1).
3. Distribution according to traffic accident characteristics
Among the accident types, 286 cases (83.63%) were caused by collisions between vehicles. Among them, 218 (63.74%), 36 (10.53%), 14 (4.09%), and 18 (5.26%) cases were rear, lateral, forward, and multiple collisions, respectively. Furthermore, 23 accidents were between vehicles and pedestrians (6.73%), 24 were between vehicles and motorcycles (7.02%), three were between vehicles and bicycles (0.88%), and six occurred while on a bus (1.75%). The distribution according to the location at the time of the accident included 257 cases in driver seats (75.15%), 17 in passenger seats (4.97%), 12 in back seats (3.51%), 23 pedestrians (6.73%), 27 motorcycles or bicycles (7.89%), and five bus passengers (0.39%) (Table 2).
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*Multiple choices were allowed for ‘symptoms’ and ‘disease code’..
&md=tbl&idx=2' data-target="#file-modal"">Table 2Distribution of traffic accident characteristics, symptoms, and disease codes.
Characteristics Total number (%) Traffic accident
characteristicsTraffic accident patterns Car to car Rear impact 218 (63.74) Frontal impact 14 (4.09) Side impact 36 (10.53) Multiple impact 18 (5.26) Pedestrian 23 (6.73) Car to motorbike 24 (7.02) Car to bicycle 3 (0.88) On the bus 6 (0.39) Location Driver’s seat 257 (75.15) Passenger seat 17 (4.97) Back seat 12 (3.51) Pedestrian 23 (9.30) Motorbike, bicycle 27 (7.89) Bus 6 (0.39) Symptoms* Physical symptoms Localized pain Neck & shoulder 297 (86.84) Low back & buttocks 306 (89.47) Head 202 (59.06) Knee & ankle 21 (6.14) Elbow & wrist 9 (2.63) Other 5 (1.46) Limb numbness 78 (22.8) Dizziness 156 (45.6) Fatigue 40 (11.7) Psychological symptoms Sleep disorder 41 (12.0) Chest discomfort due to stress 19 (5.7) Palpitations 16 (4.7) Disease code* S434: Sprain and strain of the shoulder joint 259 (75.73) M4836: Traumatic spondylopathy, lumbar region 224 (65.50) F072: Post-concussion syndrome 113 (33.04) S0600: Concussion, without an open intracranial wound 71 (20.76) S3350: Sprain and strain of the lumbar spine 66 (19.30) *Multiple choices were allowed for ‘symptoms’ and ‘disease code’..
4. Distribution according to symptoms and diagnosis
The symptoms were divided into physical and psychological symptoms. The major physical symptoms were localized pain in all patients, including 306 (89.47%) patients with pain in the lumbar and pelvic region, 297 (86.84%) with pain in the cervical spine and shoulders, 202 (59.06%) with headaches, 21 (6.14%) with pain in the knee and ankle, 9 (2.63%) with pain in the wrist and elbow, and 5 (1.46%) with other symptoms. Dizziness, limb numbness, and fatigue were reported in 156 (45.6%), 78 (22.8%), and 40 (11.7%) cases, respectively. Other symptoms included tinnitus, jaw joint problems, and digestive problems. The major psychological symptoms were sleep disorders (41 cases, 12.0%), chest discomfort (19 cases, 5.7%), palpitations (16 cases, 4.7%), followed by a sign of surprise, memory disorders, emotional control disorders, anxiety, depression, stress, and other symptoms.
Among disease code distributions, duplication of cases with two or more diagnosed cases showed sprain to be the most common, with the major disease codes being S434 (sprain and strain of shoulder joint), M4836 (traumatic spondylopathy, lumbar region), F072 (postconcussional syndrome), S0600 (concussion, without open intracranial wound), and S3350 (sprain and strain of the lumbar spine) (Table 2).
5. Distribution according to treatment duration and number of treatments
A total of 218 patients (63.74%) sought treatment within 1 month, including 57 patients (20.46%) within 2 weeks, 64 (18.71%) within 1 month, 44 (12.87%) within 3 weeks, and 40 (11.70%) within 1 week. Furthermore, 67 (19.59%) patients sought treatment within 2 months, 29 (8.48%) within 3 months, 10 (2.92%) within 4 months, and 18 (5.26%) after 4 months or more. Most patients (204, 59.65%) received fewer than 10 treatments; 90 (16.67%), 27 (7.89%), and 21 (6.14%) patients received fewer than 20, fewer than 30, and more than 30 treatments, respectively (Table 3).
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&md=tbl&idx=3' data-target="#file-modal"">Table 3
Distribution of treatment duration, number of treatments, and treatment method.
Characteristics Total number (%) Treatment duration ≤ 1 week 40 (11.70) ≤ 2 weeks 57 (20.46) ≤ 3 weeks 44 (12.87) ≤ 1 month 64 (18.71) ≤ 2 months 67 (19.59) ≤ 3 months 29 (8.48) ≤ 4 months 10 (2.92) ≥ 4 months 18 (5.26) Number of treatments ≤ 10 204 (59.65) ≤ 20 90 (16.67) ≤ 30 27 (7.89) 30 < 21 (6.14) Treatment method Acupuncture 341 (99.71) Herbal medicine 251 (73.39) Pharmacopuncture Total pharmacopuncture types
used for treatment1 126 (36.84) 2 109 (31.87) ≥ 3 105 (30.70) Type of pharmacopuncture TA 180 (58.44) HO 119 (38.64) CH 87 (28.25) MOK 85 (27.60) Others 46 (13.45) Chuna 153 (44.74) TKM physiotherapy 298 (87.13) TKM, traditional Korean medicine; TA, a pharmacopuncture medicine which was named after traffic accidents and consists of Scutellaria baicalensis, Phellodendron amurense, Pulsatilla koreana, Sophorae Tonkinensis Radix et Rhizoma, Aucklandia lappa, and Carthamus tinctorius L.; HO, a pharmacopuncture medicine which was named after Honghwaja (Carthamus tinctorius L); CH, a pharmacopuncture medicine which was named after channel, developed to control pain using sodium channels by adding salt and consists of Moschus, Ursi Fel, Bovis Calclus, Scutellaria baicalensis, Phellodendron amurense, Pulsatilla koreana, Sophorae Tonkinensis Radix et Rhizoma, Aucklandia lappa, and salt; MOK, a pharmacopuncture medicine which was commonly used to treat clinical symptoms related to heart and thyroid diseases and consists of Moschus, Ursi Fel, Bovis Calclus, Scutellaria baicalensis, Phellodendron amurense, Pulsatilla koreana, Sophorae Tonkinensis Radix et Rhizoma, Aucklandia lappa, and Hominis Placenta..
6. Distribution of treatment methods
A total of 341 patients (99.71%) received acupuncture, 251 (73.39%) were prescribed herbal medicine, 340 (99.42%) received pharmacopuncture, 298 (87.13%) received KM physiotherapy, and 153 (44.74%) received chuna therapy. Among patients receiving pharmacopuncture medicine, 126 (36.84%), 109 (31.87%), and 105 (30.70%) received one, two, or three or more types of pharmacopuncture. Regarding the types of pharmacopuncture used, when including duplicated pharmacopuncture, there were 180 (52.63%) cases of TA named after traffic accidents (Scutellaria baicalensis, Phellodendron amurense, Pulsatilla koreana, Sophorae Tonkinensis Radix et Rhizoma, Aucklandia lappa, and Carthamus tinctorius L.), 119 (34.80%) cases of HO named after Honghwaja (Carthamus tinctorius L), 87 (25.44%) cases of CH named after channel and developed to control pain using sodium channels by adding salt (Moschus, Ursi Fel, Bovis Calclus, Scutellaria baicalensis, Phellodendron amurense, Pulsatilla koreana, Sophorae Tonkinensis Radix et Rhizoma, Aucklandia lappa, and salt), 85 (24.85%) cases of MOK commonly used to treat clinical symptoms related to heart and thyroid diseases (Moschus, Ursi Fel, Bovis Calclus, Scutellaria baicalensis, Phellodendron amurense, Pulsatilla koreana, Sophorae Tonkinensis Radix et Rhizoma, Aucklandia lappa, and Hominis Placenta), and 46 other pharmacopuncture cases (13.45%) (Table 3). Pharmacopuncture used was manufactured at Namsangcheon extramural herbal medicine Dispensary (Yongin, Korea).
7. Treatment duration and number of treatments, NRS before and after treatment, and symptom improvement for each characteristic
1) Overall resultsThe mean treatment duration and number of treatments for all patients were 37.68 ± 45.11 days and 11.68 ± 10.63 treatments, respectively. The initial NRS was 7.32 ± 0.96 and decreased to 3.57 ± 1.40 at the end of treatment, with a symptom improvement score of 1.87 ± 0.60 (Table 4).
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&md=tbl&idx=4' data-target="#file-modal"">Table 4NRS, numerical rating scale..
Treatment duration, number of treatments, NRS, and improvement score according to demographic characteristics.
Treatment
durationNumber of treatments Initial NRS Posttreatment NRS Symptom improvement Sex Male (n = 209) 32.90 ± 35.09 10.62 ± 9.05 7.27 ± 0.94 3.53 ± 1.45 1.84 ± 0.63 Female (n = 138) 45.18 ± 56.92 13.35 ± 12.62 7.39 ± 0.98 3.64 ± 1.30 1.91 ± 0.55 p-value 0.000** 0.008** 0.740 0.173 0.032* Age (years) < 30 (n = 72) 42.92 ± 60.84 11.43 ± 11.92 7.31 ± 0.97 3.49 ± 1.45 1.81 ± 0.54 30 ≤, <40 (n = 137) 29.85 ± 34.29 9.78 ± 9.14 7.25 ± 0.93 3.84 ± 1.43 1.95 ± 0.61 40 ≤, <50 (n = 79) 37.67 ± 38.87 11.99 ± 9.08 7.37 ± 1.04 3.34 ± 1.25 1.84 ± 0.64 50 ≤, <60 (n = 36) 50.25 ± 47.59 16.83 ± 14.28 7.44 ± 0.80 3.21 ± 1.18 1.72 ± 0.56 60 ≤ (n = 18) 51.11 ± 57.85 15.44 ± 10.65 7.42 ± 0.89 3.61 ± 1.46 1.94 ± 0.62 p-value 0.001** 0.004** 0.798 0.333 0.823 All (n = 342) 37.68 ± 45.11 11.68 ± 10.63 7.32 ± 0.96 3.57 ± 1.40 1.87 ± 0.61 Values are mean ± SD. Statistical analyses were performed using independent two-sample t–tests or analysis of variance (ANOVA). *p < 0.05 and **p < 0.01..
NRS, numerical rating scale..
The mean treatment duration and number of treatments in men was 32.90 ± 35.09 days and 10.62 ± 9.05 treatments, respectively. The NRS decreased from 7.27 ± 0.94 to 3.53 ± 1.45, with an improvement score of 1.84 ± 0.63. In women, the mean treatment duration and number of treatments were 45.18 ± 56.92 days and 13.35 ± 12.62 treatments, respectively. The NRS decreased from 7.39 ± 0.98 to 3.64 ± 1.30, with an improvement score of 1.91 ± 0.55. Significant differences were observed in treatment duration (p < 0.01) and number of treatments (p < 0.01).
The mean treatment duration and number of treatments in patients less than 30 years of age was 42.92 ± 60.84 days and 11.43 ± 11.92 treatments, respectively. The NRS decreased from 7.31 ± 0.97 to 3.49 ± 1.45, with an improvement score of 1.81 ± 0.54. Among patients in their 30s, the mean treatment duration and number of treatments were 29.85 ± 34.29 days and 9.78 ± 9.14 treatments, respectively. The NRS decreased from 7.25 ± 0.93 to 3.84 ± 1.43, with an improvement score of 1.95 ± 0.61. Among patients in their 40s, the mean treatment duration and number of treatments were 37.67 ± 38.87 days and 11.99 ± 9.08 treatments, respectively. The NRS decreased from 7.37 ± 1.04 to 3.34 ± 1.25, with an improvement score of 1.84 ± 0.64. Among patients in their 50s, the mean treatment duration and number of treatments were 50.25 ± 47.59 days and 16.83 ± 14.28, respectively. The NRS decreased from 7.44 ± 0.80 to 3.21 ± 1.18, with an improvement score of 1.72 ± 0.56. Among patients in their 60s and older, the mean treatment duration and number of treatments were 51.11 ± 57.85 days, and 15.44 ± 10.65 treatments, respectively. The NRS decreased from 7.42 ± 0.89 to 3.61 ± 1.46, with an improvement score of 1.94 ± 0.62. Significant differences were observed in treatment duration (p < 0.01) and number of treatments (p < 0.01) according to patient age (Table 4).
3) Treatment results according to disease durationThe mean treatment duration and number of treatments during the most acute phase (within 1 week) was 33.49 ± 40.23 days and 11.58 ± 11.01 treatments, respectively. The NRS decreased from 7.30 ± 0.94 to 3.52 ± 1.41, with an improvement score of 1.86 ± 0.60. In the acute phase (within 1 week-1 month), the mean treatment duration and number of treatments were 41.89 ± 46.72 days and 11.00 ± 8.99 treatments, respectively. The NRS decreased from 7.37 ± 1.02 to 3.78 ± 1.37, with an improvement score of 1.94 ± 0.64. In the subacute stages (1-6 months after onset), the mean treatment duration and number of treatments were 84.79 ± 80.44 days and 17.43 ± 12.62, respectively. The NRS decreased from 7.39 ± 0.81 to 3.43 ± 1.10, with an improvement score of 1.71 ± 0.45. Significant differences in mean treatment duration (p < 0.01) and number of treatments (p < 0.01) were observed according to the disease duration but not for NRS change and the improvement score (Table 5).
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&md=tbl&idx=5' data-target="#file-modal"">Table 5NRS, numerical rating scale..
Treatment duration, number of treatments, NRS, and improvement score according to disease duration and traffic accident characteristics.
Treatment duration Number of treatments Initial NRS Posttreatment NRS Symptom improvement Mean ± SD Disease duration Within 1 week (n = 242) 33.49 ± 40.23 11.58 ± 11.01 7.30 ± 0.94 3.51 ± 1.41 1.86 ± 0.60 Acute stage (n = 87) 41.89 ± 46.72 11.00 ± 8.99 7.37 ± 1.02 3.78 ± 1.37 1.94 ± 0.64 Subacute stage (n = 13) 84.79 ± 80.44 17.43 ± 12.62 7.39 ± 0.81 3.43 ± 1.10 1.71 ± 0.45 p-value 0.001** 0.004** 0.902 0.957 0.852 Traffic accident situation Traffic accident patterns Rear impact (n = 218) 35.73 ± 38.40 11.73 ± 10.54 7.28 ± 0.97 3.52 ± 1.32 1.85 ± 0.57 Frontal impact (n = 14) 29.50 ± 29.81 10.21 ± 6.90 7.25 ± 0.87 3.5 ± 1.41 1.86 ± 0.83 Side impact (n = 36) 26.31 ± 22.84 8.08 ± 5.51 7.38 ± 0.85 3.64 ± 1.52 1.86 ± 0.63 Multiple impact (n = 18) 25.83 ± 24.46 8.11 ± 5.87 7.56 ± 0.90 4.47 ± 1.65 2.11 ± 0.57 Pedestrian (n = 23) 97.57 ± 94.88 21.61 ± 16.55 7.63 ± 0.85 3.24 ± 1.20 1.70 ± 0.55 Motorbike, bicycle, others (n = 27) 25.85 ± 25.97 9.63 ± 6.67 7.06 ± 0.95 3.69 ± 1.5 1.96 ± 0.69 On the bus (n = 6) 55.17 ± 68.40 17.00 ± 19.03 7.33 ± 1.18 3.5 ± 1.04 2 ± 0.58 p-value 0.070 0.347 0.296 0.276 0.665 Location Driver (n = 257) 34.26 ± 35.77 11.25 ± 9.92 7.33 ± 0.95 3.61 ± 1.42 1.89 ± 0.61 Passenger (n = 17) 23.65 ± 14.12 7.35 ± 4.90 7.50 ± 0.87 3.71 ± 1.48 1.82 ± 0.53 Back (n = 12) 25.00 ± 31.80 7.92 ± 5.71 7.04 ± 1.12 3.38 ± 0.88 1.67 ± 0.49 Pedestrian (n = 23) 97.57 ± 94.88 21.61 ± 16.55 7.63 ± 0.85 3.24 ± 1.20 1.70 ± 0.55 Motorbike, bicycle, others (n = 27) 25.85 ± 25.97 9.63 ± 6.67 7.06 ± 0.95 3.69 ± 1.5 1.96 ± 0.69 Bus (n = 6) 55.17 ± 68.40 17.00 ± 19.03 7.33 ± 1.18 3.5 ± 1.04 2 ± 0.58 p-value 0.004** 0.034* 0.238 0.843 0.542 Values are mean ± SD. Statistical analyses were performed using analysis of variance (ANOVA). *p < 0.05 and **p < 0.01..
NRS, numerical rating scale..
Among the accident types, the mean treatment duration and number of treatments in rear collision were 35.73 ± 38.40 days and 11.73 ± 10.54 treatments, respectively. The NRS decreased from 7.28 ± 0.97 to 3.52 ± 1.32, with an improvement score of 1.85 ± 0.57. For forward collisions, the mean treatment duration and number of treatments were 29.50 ± 29.81 days and 10.21 ± 6.90 treatments, respectively. The NRS decreased from 7.25 ± 0.87 to 3.5 ± 1.41, with an improvement score of 1.86 ± 0.83. For lateral collision, the mean treatment duration and number of treatments were 26.31 ± 22.84 days and 8.08 ± 5.51, respectively. The NRS decreased from 7.38 ± 0.85 to 3.64 ± 1.52, with an improvement score of 1.86 ± 0.63. For multi-collision, the mean treatment duration and number of treatments were 97.57 ± 94.88 days and 21.61 ± 16.55 treatments, respectively. The NRS decreased from 7.56 ± 0.90 to 4.47 ± 1.65, with an improvement score of 2.11 ± 0.57. For pedestrian accidents, the mean treatment duration and number of treatments were 33.49 ± 40.23 days and 11.58 ± 11.01, respectively. The NRS decreased from 7.63 ± 0.85 to 3.24 ± 1.20, with an improvement score of 1.70 ± 0.55. For vehicle and motorcycle accidents, the mean treatment duration and number of treatments were 25.85 ± 25.97 days and 9.63 ± 6.67 treatments, respectively. The NRS decreased from 7.06 ± 0.95 to 3.69 ± 1.53, with an improvement score of 1.96 ± 0.69. For bus passengers, the mean treatment duration and number of treatments were 55.17 ± 68.40 days, and 17.00 ± 19.03, respectively. The NRS decreased from 7.33 ± 1.18 to 3.5 ± 1.04, with an improvement score of 2 ± 0.58. No significant differences were observed in treatment duration, number of treatments, NRS before and after treatment, or improvement according to the accident type.
Among locations at the time of the accident, the mean treatment duration and number of treatments were 34.26 ± 35.77 days and 11.25 ± 9.92 treatments, respectively, for the driver seat. The NRS decreased from 7.33 ± 0.95 to 3.61 ± 1.42, with an improvement score of 1.89 ± 0.61. For the passenger seat, the mean treatment duration and number of treatments were 23.65 ± 14.12 days and 7.35 ± 4.90 treatments, respectively. The NRS decreased from 7.50 ± 0.87 to 3.71 ± 1.48, with an improvement score of 1.82 ± 0.53. For the rear seat, the mean treatment duration and number of treatments were 25.00 ± 31.80 days and 7.92 ± 5.71, respectively. The NRS decreased from 7.04 ± 1.12 to 3.38 ± 0.88, with an improvement score of 1.67 ± 0.49. Significant differences were observed in treatment duration (p < 0.01) and number of treatments (p < 0.01) according to the location at the time of the accident, but not for NRS before and after treatment or improvement score (Table 5).
5) Treatment results according to the presence of symptoms other than pain and psychological symptomsIn the presence of additional symptoms, the mean treatment duration and number of treatments were 40.24 ± 48.57 days and 12.51 ± 11.62, respectively. The NRS decreased from 7.34 ± 1.01 to 3.53 ± 1.36, with an improvement score of 1.87 ± 0.61. In the absence of additional symptoms, the mean treatment duration and number of treatments were 29.69 ± 31.30 days and 9.07 ± 6.13, respectively. The NRS decreased from 7.24 ± 0.75 to 3.72 ± 1.50, with an improvement score of 1.95 ± 0.66. Significant differences were observed for treatment duration (p < 0.05), number of treatments (p < 0.05), and pre (p < 0.01) and post-treatment NRS (p < 0.05).
The average treatment duration and number of treatments in patients with psychological symptoms, were 44.74 ± 58.72 days and 14.28 ± 14.74 treatments, respectively. The NRS decreased from 7.34 ± 1.01 to 3.53 ± 1.36, with an improvement score of. 1.87 ± 0.61. In the absence of psychological symptoms, the mean treatment duration and number of treatments were 35.72 ± 40.58 days and 10.96 ± 9.11 treatments, respectively. The initial NRS decreased from 7.24 ± 0.75 to 3.72 ± 1.50, with an improvement score of 1.95 ± 0.66. Significant differences in treatment duration (p < 0.05) and number of treatments (p < 0.01) were observed according to the presence of psychological symptoms but not for NRS and improvement score (Table 6).
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&md=tbl&idx=6' data-target="#file-modal"">Table 6NRS, numerical rating scale..
Treatment duration and number, NRS, and improvement according to additional symptoms, psychological symptoms, and chuna.
Treatment
durationNumber of treatments Initial NRS Posttreatment NRS Symptom improvement Mean ± SD Additional symptoms Yes (n = 259) 40.24 ± 48.57 12.51 ± 11.62 7.34 ± 1.01 3.53 ± 1.36 1.87 ± 0.61 No (n = 83) 29.69 ± 31.30 9.07 ± 6.13 7.24 ± 0.75 3.72 ± 1.50 1.95 ± 0.66 p-value 0.017* 0.010* 0.001** 0.038* 0.476 Psychological symptoms Yes (n = 74) 44.74 ± 58.72 14.28 ± 14.74 7.34 ± 0.94 3.54 ± 1.41 1.86 ± 0.56 No (n = 268) 35.72 ± 40.58 10.96 ± 9.11 7.31 ± 0.96 3.58 ± 1.40 1.87 ± 0.62 p-value 0.006** 0.017* 0.897 0.774 0.589 Chuna Yes (n = 153) 54.58 ± 50.25 17.84 ± 11.80 7.67 ± 0.91 3.21 ± 1.10 1.71 ± 0.55 No (n = 185) 23.25 ± 34.62 6.38 ± 5.52 7.01 ± 0.89 3.89 ± 1.54 2.01 ± 0.62 p-value 0.000** 0.005** 0.767 0.000** 0.023* Values are mean ± SD. Statistical analyses were performed using the independent two-sample t–tests. *p < 0.05 and **p < 0.01..
NRS, numerical rating scale..
The mean duration and number of chuna treatments were 54.58 ± 50.25 days and 17.84 ± 11.80, respectively. The NRS decreased from 7.67 ± 0.91 to 3.21 ± 1.10, with an improvement score of 1.71 ± 0.55. In cases without chuna treatment, the mean treatment duration and number of treatments were 23.25 ± 34.62 days and 6.38 ± 5.52, respectively. The NRS decreased from 7.01 ± 0.89 to 3.89 ± 1.54, with an improvement score of 2.01 ± 0.62. No significant difference in NRS was observed before treatment; however, significant differences were observed in treatment duration (p < 0.01), number of treatments (p < 0.01), post-treatment NRS (p < 0.01), and improvement score (p < 0.05) (Table 6).
7) Treatment results according to the treatment number and durationAnalysis of the number of treatments showed an NRS decrease from 7.01 ± 0.90 to 3.91 ± 1.55 and an improvement score of 2.02 ± 0.63 for 10 or fewer treatments. For 20 or fewer treatments, the NRS decreased from 7.7 ± 0.84 to 3.13 ± 0.93, with an improvement score of 1.72 ± 0.45. For 30 or fewer treatments, the NRS decreased from 7.83 ± 0.81 to 2.89 ± 0.93, with an improvement score of 1.44 ± 0.50. Finally, for more than 30 treatments, the NRS decreased from 8.02 ± 0.85 to 3.10 ± 0.92, with an improvement score of 1.57 ± 0.49. Significant differences were observed in initial NRS (p < 0.01), and improvement score (p < 0.05).
Analysis of the treatment period showed that NRS decreased from 7.07 ± 0.90 to 3.81 ± 1.53, with an improvement score of 1.96 ± 0.64 within one month. Within 2 months, the NRS decreased from 7.59 ± 0.85 to 3.12 ± 1.06, with an improvement score of 1.76 ± 0.52. Within 3 months, the NRS decreased from 8 ± 0.80 to 3.43 ± 1.00, with an improvement score of 1.76 ± 0.43. Within 4 months, the NRS decreased from 8.05 ± 0.93 to 2.7 ± 0.6, with an improvement score of 1.3 ± 0.46. Finally, for more than 4 months, the NRS decreased from 7.81 ± 0.99 to 3.11 ± 0.72, with an improvement score of 1.67 ± 0.47. Significant difference in NRS was observed before treatment (p < 0.01); however, no significant differences were observed in post-treatment NRS and improvement score (Table 7).
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&md=tbl&idx=7' data-target="#file-modal"">Table 7NRS, numerical rating scale..
NRS, and improvement score according to treatment duration and number of treatments.
Initial NRS Posttreatment NRS Symptom improvement Mean ± SD Number of treatment ≤ 10 (n = 204) 7.01 ± 0.90 3.91 ± 1.55 2.02 ± 0.63 ≤ 20 (n = 90) 7.7 ± 0.84 3.13 ± 0.93 1.72 ± 0.45 ≤ 30 (n = 27) 7.83 ± 0.81 2.89 ± 0.93 1.44 ± 0.50 > 30 (n = 21) 8.02 ± 0.85 3.10 ± 0.92 1.57 ± 0.49 p-value 0.002** 0.952 0.041* Period of treatment ≤ 1 month (n = 205) ≤ 1 week (n = 40) 7.07 ± 0.90 6.96 ± 0.90 3.81 ± 1.53 4.96 ± 1.35 1.96 ± 0.64 2.35 ± 0.61 ≤ 2 week (n = 57) 6.86 ± 0.98 3.94 ± 1.52 2.06 ± 0.65 ≤ 3 week (n = 44) 7.16 ± 0.90 3.26 ± 1.35 1.75 ± 0.53 ≤ 1 month (n = 64) 7.30 ± 0.74 3.32 ± 1.32 1.75 ± 0.5 ≤ 2 month (n = 67) 7.59 ± 0.85 3.12 ± 1.06 1.76 ± 0.5 ≤ 3 month (n = 29) 8 ± 0.80 3.43 ± 1.00 1.76 ± 0.43 ≤ 4 month (n = 10) 8.05 ± 0.93 2.7 ± 0.6 1.3 ± 0.46 ≥ 4 month (n = 18) 7.81 ± 0.99 3.11 ± 0.72 1.67 ± 0.47 p-value 0.002** 0.131 0.212 Values are mean ± SD. Statistical analyses were performed using analysis of variance (ANOVA). *p < 0.05 and **p < 0.01..
NRS, numerical rating scale..
The treatment number and duration were significantly positively correlated with initial NRS (both p < 0.001) and significantly negatively correlated with post-treatment NRS (p < 0.001, p < 0.001) and improvement score (both p < 0.001). The higher the number of treatments and the longer the treatment duration, the higher the initial NRS, lower the post-treatment NRS, and the better the improvement score (Table 8).
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Statistical significance was evaluated by Pearson’s correlation analysis..
r: correlation. p: p-value. **p < 0.01..
&md=tbl&idx=8' data-target="#file-modal"">Table 8NRS, numerical rating scale..
Correlation analysis between treatment period and number, NRS, and improvement.
Number of treatments Treatment period Initial NRS Post-treatment NRS Symptom improvement r (p) Number of treatments 1 0.815** (0.000) 0.304** (0.000) –0.205** (0.000) –0.216** (0.000) Treatment period 1 0.353** (0.000) –0.290** (0.000) –0.308** (0.000) Initial NRS 1 0.154** (0.004) –0.140** (0.010) Posttreatment NRS 1 0.764** (0.000) Symptom improvement 1 Statistical significance was evaluated by Pearson’s correlation analysis..
r: correlation. p: p-value. **p < 0.01..
NRS, numerical rating scale..
A total of 340 patients received pharmacopuncture. In December 2017, TA pharmacopuncture was developed to treat traffic accident patients. We investigated the use of pharmacopuncture. Before the introduction of TA pharmacopuncture, 10 (7.81%), 49 (38.28%), and 69 cases (53.91%) received one, two, or three or more types of acupuncture, respectively. After the introduction of TA pharmacopuncture, 116 (54.72%), 60 (28.30%), and 36 (16.98%) cases received one, two, or three or more types of acupuncture, respectively. Since the introduction of TA pharmacopuncture, the rate of use of one type of pharmacopuncture increased from 7.81% to 54.72%. Before using TA pharmacopuncture, the mean treatment duration and number of treatments were 38.17 ± 50.62 days and 11.15 ± 10.39, respectively; the NRS decreased from 7.32 ± 0.97 to 3.54 ± 1.42, with and an improvement score of 1.85 ± 0.63. After the introduction of TA pharmacopuncture, the treatment duration and number of treatments were 37.48 ± 41.87 days and 12.01 ± 10.85, respectively; the NRS decreased from 7.32 ± 0.95 to 3.59 ± 1.3, with an improvement score of 1.88 ± 0.56. No significant differences were observed between treatment groups before and after TA pharmacopuncture in treatment duration and number, NRS before and after treatment, and improvement score (Table 9).
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TA: a pharmacopuncture extract named for traffic accidents consisting of Scutellaria baicalensis, Phellodendron amurense, Pulsatilla koreana, Sophora tonkinensis, Aucklandia lappa, Aquilaria agallocha, and Carthamus tinctorius L..
&md=tbl&idx=9' data-target="#file-modal"">Table 9NRS, numerical rating scale..
Use of main pharmacopuncture methods.
Total number of pharmacopuncture types
used for treatmentTreatment period (days) Number of treatments Initial NRS Post-treatment NRS Symptom
improvementMean ± SD Using TA Before (n = 128) 1 (n = 10) 39.70 ± 45.60 7.50 ± 6.62 7.15 ± 0.85 3.90 ± 1.76 2.00 ± 0.82 2 (n = 49) 40.43 ± 59.38 12.06 ± 12.83 7.41 ± 0.98 3.67 ± 1.54 1.90 ± 0.65 3 or more (n = 69) 36.35 ± 44.87 10.97 ± 8.81 7.22 ± 0.97 3.38 ± 1.28 1.81 ± 0.60 38.17 ± 50.62 11.15 ± 10.39 7.32 ± 0.97 3.54 ± 1.42 1.85 ± 0.63 After (n = 212) 1 (n = 116) 26.26 ± 29.46 8.46 ± 7.14 7.12 ± 0.92 3.79 ± 1.43 1.99 ± 1.67 2 (n = 60) 45.05 ± 54.71 14.10 ± 12.51 7.51 ± 1.01 3.14 ± 1.24 1.67 ± 0.51 3 or more (n = 36) 61.03 ± 39.85 20.08 ± 12.66 7.74 ± 0.78 3.68 ± 1.35 1.83 ± 0.51 37.48 ± 41.87 12.01 ± 10.85 7.32 ± 0.95 3.59 ± 1.39 1.88 ± 0.56 p-value 0.325 0.331 0.524 0.843 0.337 Total (n = 340) 37.74 ± 45.29 11.69 ± 10.67 7.32 ± 0.96 3.57 ± 1.40 1.87 ± 0.61 Values are mean ± SD. Statistical analyses were performed using independent two-sample t–tests. *p < 0.05 and **p < 0.01..
TA: a pharmacopuncture extract named for traffic accidents consisting of Scutellaria baicalensis, Phellodendron amurense, Pulsatilla koreana, Sophora tonkinensis, Aucklandia lappa, Aquilaria agallocha, and Carthamus tinctorius L..
NRS, numerical rating scale..
No adverse reactions including infection, bleeding, hematoma, fatigue, sweating, severe nausea, dizziness, and headache, were observed for any treatment. Sixteen cases of pain, 16 cases of body ache, 10 cases of tingling feelings, and one case of tingling skin were reported during treatment. The treatment rejections included three pharmacopuncture treatment rejections, one CP pharmacopuncture medicine rejection, one electro-acupuncture treatment rejection, and one rejection for all kinds of needle treatment.
DISCUSSION
Traffic accidents are a social problem that poses a serious threat to people’s lives, causing pain and mental anguish for the victims and their families. Furthermore, the number of traffic accident patients and medical expenses are rising due to increased automobile use. The number of patients visiting KM institutions is constantly increasing due to KM automobile insurance coverage and patient satisfaction for the treatment of traffic accidents; moreover, to compensate for the lack of treatment in WM institutions, traffic accident patients often chose KM treatment such as acupuncture, herbal medicine, chuna, and pharmacopuncture, and they experience satisfaction after treatment and showed self-diffusion and ambient diffusion for KM treatment [8, 12]. Various domestic and international clinical and experimental studies have assessed the effects of KM treatment for treating traffic accident injury syndrome, and more patients are expected to use KM treatment in the future [12, 13]. However, there are few reports related to automobile insurance care at KM clinics, which was ranked first among medical billing by type of medical institution [9]; thus, there is a need to determine the medical status at KM Clinics. Therefore, this study investigated the medical status of 342 traffic accident patients who visited the Jisung Kyunghee KM clinic between January 1, 2017, and June 30, 2019.
Of the 342 patients, 209 (61.11%) were men and 138 (38.99%) were women, with men 1.51 times more predominant than women. This finding differed from those of previous reports of more female patients in car accidents in Korea [7, 8]. One explanation for this difference may be the many opportunities for treatment of male patients in the present study because our clinic is located in a city with many floating populations. In terms of age distribution, patients in their 30s and 40s accounted for about 63% of the patient population and patients in their 20s-50s accounted for about 95% of the total. This finding is concordant with that of previous reports suggesting the greatest risk of traffic accidents in the age groups which is the main cause of social activity [11], in which there are not only many drivers in the younger age groups but also concern regarding the aftermath of traffic accidents. No significant differences in NRS before and after treatment or improvement score was observed according to sex and age, but a statistically significant difference was observed for treatment duration and number of treatments. The significantly higher treatment period and number of treatments in women compared to those in men may be linked to the results of previous studies reporting that women have a lower employment rate than men, have more time for treatment, and are more susceptible to trauma and the aftereffects of traffic accidents [14, 15].
The treatment period and number of treatments were lowest in patients in their 30s and were lower for patients in their 20s and 40s than for those in their 50s or older. This finding may be related to previous reports that young people are relatively active in seeking treatment because of their high level of awareness and concern about the aftereffects of car accidents, with high treatment effects in the younger individuals, while middle-aged people in their 50s and 60s and elderly people in their 80s are less resilient to the aftereffects of car accidents [16].
Previous studies on traffic accident types observed many minor injuries due to being in the driver seat and rear collision among patients receiving KM treatment [7, 8]. In the present study, rear collisions (218, 63.74%) and driver seats (257, 75.15%) were also the most common factors. There were no statistically significant differences in treatment duration and number, NRS before and after treatment, improvement score according to accident type or in NRS before and after treatment, and improvement score according to the location at the time of the accident. In terms of the treatment period and number of treatments according to the location at the time of the accident, the treatment period was significantly longer and the number of treatments were higher in the order of pedestrian, bus passenger, driver seat, motorcycle or bicycle, back seat, and passenger seat, likely because a pedestrian experienced the greatest impact of a direct collision.
The main disease codes of traffic accident patients visiting KM institutions were sprains and strains of the c-spine (S13, 56.3%), sprains and strains of the lumbar and pelvic region (S33, 25.7%), and intracranial injury (S06, 8.0%) [3, 16, 17] accompanied by localized pain in various areas and systemic and mental symptoms [6, 9, 18-20]. The present study also observed various systemic and psychological symptoms, and all patients had localized pain. Meanwhile, pain around the lumbar and pelvic region and cervical spine and shoulders were observed in that order. For most cases with combined neck and shoulder muscle soreness, our clinic used code S43.4 (sprain and strain of the shoulder joint); therefore, the main disease code differed slightly from that in the previous report. In cases with additional symptoms and mental symptoms other than pain, the treatment duration and number were significantly longer; moreover, the NRS before treatment was larger in patients with additional symptoms. Therefore, the presence of symptoms other than pain may predict treatment duration and frequency.
Previous studies reported that most accidents on roads are minor [21]. Most patients who visit KM institutions are diagnosed with simple sprains owing to the characteristics of KM treatment that the primary care in WM hospitals excludes serious damage because that the more severe the pain after a traffic accident, the more often the first visit to WM hospital is chose [6, 8]. In our study, 134 patients (39.18%) visited our clinic first following a traffic accident, a finding likely to be the result of simple sprain in patients with minor accidents based on previous reports. Before coming to our clinic, 106 patients (30.99%) had been treated and tested at WM institutions and 52 (15.20%) were only tested at WM institutions, a finding consistent with those of a survey on KM use and herbal medicine consumption in 2017, in which 50.4% of KM outpatients first presented to other medical institutions, mainly WM clinics (55.4%), for treatment of the same symptoms. In previous studies, most traffic accident patients who visited KM institutions first presented to WM hospitals, which was attributed to psychological factors of the victims and perpetrators who preferred WM examination even though their symptoms were minor [6, 9]. The perspectives of these previous studies can be applied in the present study.
Regarding the motivation for selecting our clinic, 197 patients (57.60%) visited through an internet search, 70 were existing patients (20.47%), 36 (10.53%) visited due to acquaintance introduction, 35 (10.23%) visited due to proximity, and four (1.17%) patients selected our clinic for other reasons. A survey on KM use and herbal medicine consumption in 2017 reported that 34.9% of Koreans reported being aware of KM care and that information or knowledge on KM care were most commonly obtained from neighbors such as family and friends (38.6%), followed by broadcasting media (27.3%) and KM institutions (24.9%) [22]. Internet searches were likely the main motive for visiting our clinic because the market for KM automobile insurance has grown recently, and patients reportedly have high awareness and satisfaction with KM automobile insurance care [8]. Moreover, KM institutions are actively promoting and providing information, including in networks related to traffic accidents.
Regarding the duration of disease before presenting to our clinic, most patients (242, 70.76%) reported during the acute phase (within 1 week), and patients with acute and subacute phases had passed through other medical institutions during the most acute phase. Most patients likely visited medical institutions during the most acute phase because both the victim and offender felt the need for prompt treatment due to mental shock and discomfort in daily life immediately after the accident, in addition to psychological factors associated with compensation issues with auto insurance companies. No significant difference in NRS before and after treatment and improvement score according to the duration of disease were observed; however, a longer disease duration was associated with a longer treatment duration and higher number of treatments. Prospective studies have reported that most recoveries occur up to 3 months after the initial injury [23, 24]; thus, appropriate care management is important in the acute and subacute stages to prevent the development of chronic diseases [18]. To prevent the disease from becoming chronic, treatment should be started soon after the traffic accident.
Assessment of the distribution of treatment period showed that the majority of patients (218, 63.74%) completed treatment within 1 month, a finding concordant with those of previous reports from KM institutions that treatment rarely lasts for more than 1 month [9]. The average number of treatments was 11.68 ± 10.63; 204 (59.65%) and 90 (16.67%) patients received fewer than 10 and 20 treatments, respectively. This is consistent with a report indicating an average of 11.6 outpatient visits to KM in the past year in a survey of KM use and herbal medicine consumption in 2017 [22]. Furthermore, considering the treatment period, the number of treatments was not high because most patients could not attend daily due to social activities. The initial NRS of all patients, 7.32 ± 0.96, decreased to 3.57 ± 1.40 at the end of treatment; the improvement score, 1.87 ± 0.60, was between ① Excellent and ② Good. Analysis of the correlation between treatment duration and number, NRS change, and improvement score showed that the higher the number of treatments and the longer treatment duration, the higher the initial NRS, the lower the NRS after treatment, and the better the improvement score. This finding was related to that of a previous report demonstrating that the recovery rate was not constant in cases of prolonged treatment and depended on the degree of injury; furthermore, recovery was delayed due to social activities or labor during outpatient treatment [6]. Furthermore, this is thought to be an extension of the treatment period due to the severity of the treatment, rather than long-term treatment because the treatment effect is weak, given the NRS change and improvement scores.
Pharmacopuncture is a new acupuncture treatment combining acupuncture and herbal medicines that has been used for almost all types of diseases in KM clinical practice and is the second-most common treatment after acupuncture in traffic accident patients [8, 16]. In particular, HO, HN, V, OK, and TA are used to treat acute or chronic inflammation and pain in patients with musculoskeletal disorders and traffic accident injury syndrome [25-27]. In our clinic, 99.42% of patients were administered pharmacopuncture in the order of TA, HO, CH, and MOK, and various kinds of acupuncture were used alone or in combination during the treatment period. Chuna was performed when symptoms improved slowly or when additional treatment was needed; therefore, the number of patients treated with chuna (153 patients, 44.74%) was smaller than the number of patients receiving pharmacopuncture, and patients treated with chuna had significantly longer treatment periods and higher numbers of treatments.
In our study, TA was the most commonly used pharmacopuncture. The plant-based extract TA was developed in 2015 to replace the animal-based extracts Bovis Calculus-Ursi Fel- Moschus (BUM or V), for which it was difficult to obtain stable supplies. TN consists of Scutellariae Radix, Phellodendri Cortex, Pulsatillae Radix, Sophorae Tonkinensis Radix et Rhizoma, Aucklandiae Radix, Aquilariae Lignum, and Carthami Fructus and was named for its principal use in treating traffic accident-related injuries. TA has been experimentally confirmed to be safe; however, while its clinical use is increasing, there few clinical reports [26-28]. We started using TA pharmacopuncture in December 2017 and changed to a treatment method mainly using TA pharmacopuncture. Since TA acupuncture alone was used in more than 50% of cases, the variety of types of pharmacopuncture was less than that before TA pharmacopuncture. No statistically significant differences were observed in treatment duration and number, NRS before and after treatment, and improvement scores before and after TA pharmacopuncture, a finding that indicates the validity of the development of TA pharmacopuncture for the management of various symptoms caused by traffic accidents, with similar therapeutic effects in place of the role of various pharmacopuncture. However, additional large-scale TA pharmacopuncture-related clinical studies in traffic accident patients are warranted and, after excluding other treatments, group comparisons of the treatment effect and detailed analysis of this effect according to the pain area and symptoms should be performed.
The results of this study confirmed the high treatment effect of KM treatment under automobile insurance reported previously [6-9]. Significant correlations were also observed based on detailed medical status, which may be used as evidence to justify increased KM care in the auto insurance system. No specific adverse reactions were observed for any of the treatments, as well as no discomfort with sequelae; therefore, the safety of KM treatment for traffic accident patients was confirmed to some extent. This study was limited in that it was conducted at a single KM clinic, treatment satisfaction was not investigated, and the operator and evaluator were not blinded. In addition, due to the characteristics of general KM treatment, in which various treatment methods including acupuncture, pharmacopuncture, herbal medicine, physiotherapy, and chuna treatment are combined, the effects of each treatment method were not assessed. In order to accumulate more evidence on the therapeutic effect of oriental medicine on traffic accident injuries, it will be necessary to verify the effect of each KM treatment method and to compare the treatment effect between various KM treatment methods, and additional studies in other regions and larger, multicenter studies are needed.
CONCLUSION
This study confirmed the previous findings of a high treatment effect of KM under automobile insurance. We also observed significant correlations based on a detailed medical status, which may explain the increasing use of KM in the automobile insurance system. Additional studies in different regions and with larger and multi-center studies are needed.
CONFLICTS OF INTEREST
The authors declare that they have no conflicts of interest.
DATA AVAILABILITY
The data used to support the findings of this study are available from the corresponding author upon request.
AUTHORS’ CONTRIBUTIONS
JHH performed the data analysis and interpretation of the data. JHJ and JHH contributed to the study concept and design. JHJ conducted the study and data collection. JHH and JK performed the data analysis and interpretation of the data. JHH performed manuscript writing, and JHH and JHJ revised manuscript.
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Table 1 . Patient characteristics.
Characteristics Sex Total
number (%)Male Female Age group (years) < 30 35 (10.23) 37 (10.82) 72 (21.05) 30 ≤, < 40 97 (28.36) 40 (11.70) 137 (40.06) 40 ≤, < 50 52 (15.20) 27 (7.89) 79 (23.10) 50 ≤, < 60 20 (5.85) 16 (4.68) 36 (10.53) 60 ≤ 5 (1.46) 13 (3.80) 18 (5.26) Motivation for visiting Web search 120 (35.09) 77 (22.51) 197 (57.60) Current patient 42 (12.28) 28 (8.19) 70 (20.47) Acquaintance introduction 22 (6.43) 14 (4.09) 36 (10.53) Close distance 23 (6.73) 12 (3.51) 35 (10.23) Other 2 (0.58) 2 (0.58) 4 (1.17) Duration between
accident and visiting
our clinicWithin 1 week Accident day 19 (5.56) 9 (2.63) 242 (70.76) 1-2 days 82 (23.98) 31 (9.06) 3-7 days 54 (15.79) 37 (10.82) 1 week-1 month (Acute stage) 46 (13.45) 41 (11.99) 87 (25.44) 2-6 months (Subacute stage) 8 (2.34) 5 (1.46) 13 (3.8) Patterns of visiting
our clinicVia other
medical institutionTKM Outpatient 2 (0.58) Radioactive examination & TKM outpatient 2 (0.58) TKM hospital inpatient with radioactive examination 11 (3.22) WM Radioactive examination 52 (15.20) Discharge after admission and treatment 35 (10.23) Radioactive examination & WM outpatient 106 (30.99) Direct visit 134 (39.18) TKM, traditional Korean medicine; WM, Western medicine..
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Table 2 . Distribution of traffic accident characteristics, symptoms, and disease codes.
Characteristics Total number (%) Traffic accident
characteristicsTraffic accident patterns Car to car Rear impact 218 (63.74) Frontal impact 14 (4.09) Side impact 36 (10.53) Multiple impact 18 (5.26) Pedestrian 23 (6.73) Car to motorbike 24 (7.02) Car to bicycle 3 (0.88) On the bus 6 (0.39) Location Driver’s seat 257 (75.15) Passenger seat 17 (4.97) Back seat 12 (3.51) Pedestrian 23 (9.30) Motorbike, bicycle 27 (7.89) Bus 6 (0.39) Symptoms* Physical symptoms Localized pain Neck & shoulder 297 (86.84) Low back & buttocks 306 (89.47) Head 202 (59.06) Knee & ankle 21 (6.14) Elbow & wrist 9 (2.63) Other 5 (1.46) Limb numbness 78 (22.8) Dizziness 156 (45.6) Fatigue 40 (11.7) Psychological symptoms Sleep disorder 41 (12.0) Chest discomfort due to stress 19 (5.7) Palpitations 16 (4.7) Disease code* S434: Sprain and strain of the shoulder joint 259 (75.73) M4836: Traumatic spondylopathy, lumbar region 224 (65.50) F072: Post-concussion syndrome 113 (33.04) S0600: Concussion, without an open intracranial wound 71 (20.76) S3350: Sprain and strain of the lumbar spine 66 (19.30) *Multiple choices were allowed for ‘symptoms’ and ‘disease code’..
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Table 3 . Distribution of treatment duration, number of treatments, and treatment method.
Characteristics Total number (%) Treatment duration ≤ 1 week 40 (11.70) ≤ 2 weeks 57 (20.46) ≤ 3 weeks 44 (12.87) ≤ 1 month 64 (18.71) ≤ 2 months 67 (19.59) ≤ 3 months 29 (8.48) ≤ 4 months 10 (2.92) ≥ 4 months 18 (5.26) Number of treatments ≤ 10 204 (59.65) ≤ 20 90 (16.67) ≤ 30 27 (7.89) 30 < 21 (6.14) Treatment method Acupuncture 341 (99.71) Herbal medicine 251 (73.39) Pharmacopuncture Total pharmacopuncture types
used for treatment1 126 (36.84) 2 109 (31.87) ≥ 3 105 (30.70) Type of pharmacopuncture TA 180 (58.44) HO 119 (38.64) CH 87 (28.25) MOK 85 (27.60) Others 46 (13.45) Chuna 153 (44.74) TKM physiotherapy 298 (87.13) TKM, traditional Korean medicine; TA, a pharmacopuncture medicine which was named after traffic accidents and consists of Scutellaria baicalensis, Phellodendron amurense, Pulsatilla koreana, Sophorae Tonkinensis Radix et Rhizoma, Aucklandia lappa, and Carthamus tinctorius L.; HO, a pharmacopuncture medicine which was named after Honghwaja (Carthamus tinctorius L); CH, a pharmacopuncture medicine which was named after channel, developed to control pain using sodium channels by adding salt and consists of Moschus, Ursi Fel, Bovis Calclus, Scutellaria baicalensis, Phellodendron amurense, Pulsatilla koreana, Sophorae Tonkinensis Radix et Rhizoma, Aucklandia lappa, and salt; MOK, a pharmacopuncture medicine which was commonly used to treat clinical symptoms related to heart and thyroid diseases and consists of Moschus, Ursi Fel, Bovis Calclus, Scutellaria baicalensis, Phellodendron amurense, Pulsatilla koreana, Sophorae Tonkinensis Radix et Rhizoma, Aucklandia lappa, and Hominis Placenta..
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Table 4 . Treatment duration, number of treatments, NRS, and improvement score according to demographic characteristics.
Treatment
durationNumber of treatments Initial NRS Posttreatment NRS Symptom improvement Sex Male (n = 209) 32.90 ± 35.09 10.62 ± 9.05 7.27 ± 0.94 3.53 ± 1.45 1.84 ± 0.63 Female (n = 138) 45.18 ± 56.92 13.35 ± 12.62 7.39 ± 0.98 3.64 ± 1.30 1.91 ± 0.55 p-value 0.000** 0.008** 0.740 0.173 0.032* Age (years) < 30 (n = 72) 42.92 ± 60.84 11.43 ± 11.92 7.31 ± 0.97 3.49 ± 1.45 1.81 ± 0.54 30 ≤, <40 (n = 137) 29.85 ± 34.29 9.78 ± 9.14 7.25 ± 0.93 3.84 ± 1.43 1.95 ± 0.61 40 ≤, <50 (n = 79) 37.67 ± 38.87 11.99 ± 9.08 7.37 ± 1.04 3.34 ± 1.25 1.84 ± 0.64 50 ≤, <60 (n = 36) 50.25 ± 47.59 16.83 ± 14.28 7.44 ± 0.80 3.21 ± 1.18 1.72 ± 0.56 60 ≤ (n = 18) 51.11 ± 57.85 15.44 ± 10.65 7.42 ± 0.89 3.61 ± 1.46 1.94 ± 0.62 p-value 0.001** 0.004** 0.798 0.333 0.823 All (n = 342) 37.68 ± 45.11 11.68 ± 10.63 7.32 ± 0.96 3.57 ± 1.40 1.87 ± 0.61 Values are mean ± SD. Statistical analyses were performed using independent two-sample t–tests or analysis of variance (ANOVA). *p < 0.05 and **p < 0.01..
NRS, numerical rating scale..
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Table 5 . Treatment duration, number of treatments, NRS, and improvement score according to disease duration and traffic accident characteristics.
Treatment duration Number of treatments Initial NRS Posttreatment NRS Symptom improvement Mean ± SD Disease duration Within 1 week (n = 242) 33.49 ± 40.23 11.58 ± 11.01 7.30 ± 0.94 3.51 ± 1.41 1.86 ± 0.60 Acute stage (n = 87) 41.89 ± 46.72 11.00 ± 8.99 7.37 ± 1.02 3.78 ± 1.37 1.94 ± 0.64 Subacute stage (n = 13) 84.79 ± 80.44 17.43 ± 12.62 7.39 ± 0.81 3.43 ± 1.10 1.71 ± 0.45 p-value 0.001** 0.004** 0.902 0.957 0.852 Traffic accident situation Traffic accident patterns Rear impact (n = 218) 35.73 ± 38.40 11.73 ± 10.54 7.28 ± 0.97 3.52 ± 1.32 1.85 ± 0.57 Frontal impact (n = 14) 29.50 ± 29.81 10.21 ± 6.90 7.25 ± 0.87 3.5 ± 1.41 1.86 ± 0.83 Side impact (n = 36) 26.31 ± 22.84 8.08 ± 5.51 7.38 ± 0.85 3.64 ± 1.52 1.86 ± 0.63 Multiple impact (n = 18) 25.83 ± 24.46 8.11 ± 5.87 7.56 ± 0.90 4.47 ± 1.65 2.11 ± 0.57 Pedestrian (n = 23) 97.57 ± 94.88 21.61 ± 16.55 7.63 ± 0.85 3.24 ± 1.20 1.70 ± 0.55 Motorbike, bicycle, others (n = 27) 25.85 ± 25.97 9.63 ± 6.67 7.06 ± 0.95 3.69 ± 1.5 1.96 ± 0.69 On the bus (n = 6) 55.17 ± 68.40 17.00 ± 19.03 7.33 ± 1.18 3.5 ± 1.04 2 ± 0.58 p-value 0.070 0.347 0.296 0.276 0.665 Location Driver (n = 257) 34.26 ± 35.77 11.25 ± 9.92 7.33 ± 0.95 3.61 ± 1.42 1.89 ± 0.61 Passenger (n = 17) 23.65 ± 14.12 7.35 ± 4.90 7.50 ± 0.87 3.71 ± 1.48 1.82 ± 0.53 Back (n = 12) 25.00 ± 31.80 7.92 ± 5.71 7.04 ± 1.12 3.38 ± 0.88 1.67 ± 0.49 Pedestrian (n = 23) 97.57 ± 94.88 21.61 ± 16.55 7.63 ± 0.85 3.24 ± 1.20 1.70 ± 0.55 Motorbike, bicycle, others (n = 27) 25.85 ± 25.97 9.63 ± 6.67 7.06 ± 0.95 3.69 ± 1.5 1.96 ± 0.69 Bus (n = 6) 55.17 ± 68.40 17.00 ± 19.03 7.33 ± 1.18 3.5 ± 1.04 2 ± 0.58 p-value 0.004** 0.034* 0.238 0.843 0.542 Values are mean ± SD. Statistical analyses were performed using analysis of variance (ANOVA). *p < 0.05 and **p < 0.01..
NRS, numerical rating scale..
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Table 6 . Treatment duration and number, NRS, and improvement according to additional symptoms, psychological symptoms, and chuna.
Treatment
durationNumber of treatments Initial NRS Posttreatment NRS Symptom improvement Mean ± SD Additional symptoms Yes (n = 259) 40.24 ± 48.57 12.51 ± 11.62 7.34 ± 1.01 3.53 ± 1.36 1.87 ± 0.61 No (n = 83) 29.69 ± 31.30 9.07 ± 6.13 7.24 ± 0.75 3.72 ± 1.50 1.95 ± 0.66 p-value 0.017* 0.010* 0.001** 0.038* 0.476 Psychological symptoms Yes (n = 74) 44.74 ± 58.72 14.28 ± 14.74 7.34 ± 0.94 3.54 ± 1.41 1.86 ± 0.56 No (n = 268) 35.72 ± 40.58 10.96 ± 9.11 7.31 ± 0.96 3.58 ± 1.40 1.87 ± 0.62 p-value 0.006** 0.017* 0.897 0.774 0.589 Chuna Yes (n = 153) 54.58 ± 50.25 17.84 ± 11.80 7.67 ± 0.91 3.21 ± 1.10 1.71 ± 0.55 No (n = 185) 23.25 ± 34.62 6.38 ± 5.52 7.01 ± 0.89 3.89 ± 1.54 2.01 ± 0.62 p-value 0.000** 0.005** 0.767 0.000** 0.023* Values are mean ± SD. Statistical analyses were performed using the independent two-sample t–tests. *p < 0.05 and **p < 0.01..
NRS, numerical rating scale..
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Table 7 . NRS, and improvement score according to treatment duration and number of treatments.
Initial NRS Posttreatment NRS Symptom improvement Mean ± SD Number of treatment ≤ 10 (n = 204) 7.01 ± 0.90 3.91 ± 1.55 2.02 ± 0.63 ≤ 20 (n = 90) 7.7 ± 0.84 3.13 ± 0.93 1.72 ± 0.45 ≤ 30 (n = 27) 7.83 ± 0.81 2.89 ± 0.93 1.44 ± 0.50 > 30 (n = 21) 8.02 ± 0.85 3.10 ± 0.92 1.57 ± 0.49 p-value 0.002** 0.952 0.041* Period of treatment ≤ 1 month (n = 205) ≤ 1 week (n = 40) 7.07 ± 0.90 6.96 ± 0.90 3.81 ± 1.53 4.96 ± 1.35 1.96 ± 0.64 2.35 ± 0.61 ≤ 2 week (n = 57) 6.86 ± 0.98 3.94 ± 1.52 2.06 ± 0.65 ≤ 3 week (n = 44) 7.16 ± 0.90 3.26 ± 1.35 1.75 ± 0.53 ≤ 1 month (n = 64) 7.30 ± 0.74 3.32 ± 1.32 1.75 ± 0.5 ≤ 2 month (n = 67) 7.59 ± 0.85 3.12 ± 1.06 1.76 ± 0.5 ≤ 3 month (n = 29) 8 ± 0.80 3.43 ± 1.00 1.76 ± 0.43 ≤ 4 month (n = 10) 8.05 ± 0.93 2.7 ± 0.6 1.3 ± 0.46 ≥ 4 month (n = 18) 7.81 ± 0.99 3.11 ± 0.72 1.67 ± 0.47 p-value 0.002** 0.131 0.212 Values are mean ± SD. Statistical analyses were performed using analysis of variance (ANOVA). *p < 0.05 and **p < 0.01..
NRS, numerical rating scale..
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Table 8 . Correlation analysis between treatment period and number, NRS, and improvement.
Number of treatments Treatment period Initial NRS Post-treatment NRS Symptom improvement r (p) Number of treatments 1 0.815** (0.000) 0.304** (0.000) –0.205** (0.000) –0.216** (0.000) Treatment period 1 0.353** (0.000) –0.290** (0.000) –0.308** (0.000) Initial NRS 1 0.154** (0.004) –0.140** (0.010) Posttreatment NRS 1 0.764** (0.000) Symptom improvement 1 Statistical significance was evaluated by Pearson’s correlation analysis..
r: correlation. p: p-value. **p < 0.01..
NRS, numerical rating scale..
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Table 9 . Use of main pharmacopuncture methods.
Total number of pharmacopuncture types
used for treatmentTreatment period (days) Number of treatments Initial NRS Post-treatment NRS Symptom
improvementMean ± SD Using TA Before (n = 128) 1 (n = 10) 39.70 ± 45.60 7.50 ± 6.62 7.15 ± 0.85 3.90 ± 1.76 2.00 ± 0.82 2 (n = 49) 40.43 ± 59.38 12.06 ± 12.83 7.41 ± 0.98 3.67 ± 1.54 1.90 ± 0.65 3 or more (n = 69) 36.35 ± 44.87 10.97 ± 8.81 7.22 ± 0.97 3.38 ± 1.28 1.81 ± 0.60 38.17 ± 50.62 11.15 ± 10.39 7.32 ± 0.97 3.54 ± 1.42 1.85 ± 0.63 After (n = 212) 1 (n = 116) 26.26 ± 29.46 8.46 ± 7.14 7.12 ± 0.92 3.79 ± 1.43 1.99 ± 1.67 2 (n = 60) 45.05 ± 54.71 14.10 ± 12.51 7.51 ± 1.01 3.14 ± 1.24 1.67 ± 0.51 3 or more (n = 36) 61.03 ± 39.85 20.08 ± 12.66 7.74 ± 0.78 3.68 ± 1.35 1.83 ± 0.51 37.48 ± 41.87 12.01 ± 10.85 7.32 ± 0.95 3.59 ± 1.39 1.88 ± 0.56 p-value 0.325 0.331 0.524 0.843 0.337 Total (n = 340) 37.74 ± 45.29 11.69 ± 10.67 7.32 ± 0.96 3.57 ± 1.40 1.87 ± 0.61 Values are mean ± SD. Statistical analyses were performed using independent two-sample t–tests. *p < 0.05 and **p < 0.01..
TA: a pharmacopuncture extract named for traffic accidents consisting of Scutellaria baicalensis, Phellodendron amurense, Pulsatilla koreana, Sophora tonkinensis, Aucklandia lappa, Aquilaria agallocha, and Carthamus tinctorius L..
NRS, numerical rating scale..
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