Green synthesized iron oxide nanoparticles.|@|~(^,^)~|@|(A) Representing SEM images of green synthesized nanoparticles showing 10-50 nm in size and spherical in shape and (B) showing the state of nanoparticles as hematite (IONPs) [8, 13].|@|~(^,^)~|@|(A-D) Body weight and relative organ weight before and after oral administration of IONP at 0 and 28 days. Data are expressed as means ± SD of the mean (n = 6). α is significant at p < 0.05 relative to the control.|@|~(^,^)~|@|Histological evaluation of IONPs on various tissues. Representative images of brain, heart, kidney and liver of control, vehicle control and IONPs (1 mg/kg, 10 mg/kg, 100 mg/kg) treated groups where organs collected after 28 days of oral administration. Sections were stained with H&E and observed under a light microscope at 10X & 40X magnification.

J Pharmacopuncture 2020;23:165~172 https://doi.org/10.3831/KPI.2020.23.3.165