Cross Mark
CrossMark Policy
Crossmark
Applying the CrossMark icon is a commitment by Korea Pharmacopuncture Institute to maintain the content published and alert readers to changes if and when they occur.
What is Crossmark?
CrossMark, a multi-publisher initiative from CrossRef, provides a standard way for readers to locate the authoritative version of a document. Elsevier recognizes the importance of the integrity and completeness of the scholarly record to researchers and librarians and attaches the highest importance to maintaining trust in the authority of its electronic archive. Clicking on the CrossMark icon will inform the reader of the current status of a document and may also provide additional publication record information about the document.
Permanency of content
All content published in Journal of Pharmacopuncture is permanently published, regardless of the outcome of the peer review that follows after publication. All versions of all articles that have passed peer review are permanently archived in PubMed Central.
Authors can revise, change and update their articles by publishing new versions, which are added to the article’s history; however, the individual versions, once published, cannot be altered or withdrawn and are permanently available on the Journal of Pharmacopuncture website. Journal of Pharmacopuncture participates in the CrossMark scheme, a multi-publisher initiative that has developed a standard way for readers to locate the current version of a piece of content. By applying the CrossMark policies, Journal of Pharmacopuncture is committed to maintaining the content it publishes and to alerting readers to changes if and when they occur.
Clicking on the CrossMark logo (at the top of each Journal of Pharmacopuncture article) will give you the current status of an article and direct you to the latest published version; it may also give you additional information such as new referee reports.
In order to maintain the integrity and completeness of the scholarly record, we will apply the following policies when published content needs to be corrected; these policies take into account current best practice in the scholarly publishing and library communities:
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Correction
In traditional journals, where articles are peer-reviewed before publication, Corrections (or Errata) are published to alert readers to errors in the article that became apparent following the publication of the final article. By contrast, articles in Journal of Pharmacopuncture undergo peer review post publication and publication is not ‘final’ as new versions can be added at any stage. Possible mistakes that come to light during the peer review process may be highlighted in the published referee reports, which are part of the article. Authors can publish revised versions, and any errors that become apparent during peer review or later can be corrected through the publication of new versions. Corrections and changes relative to the previous version are always summarized in the ‘Amendments’ section at the start of a new version. -
Retraction
This action is reserved for articles that are seriously flawed and so the findings or conclusions cannot be relied upon. Articles may be retracted for several reasons, including:
• honest errors reported by the authors (for example, errors due to the mixing up of samples or use of a scientific tool or equipment that is found subsequently to be faulty)
• research misconduct (data fabrication)
• duplicate or overlapping publication
• fraudulent use of data
• plagiarism
• unethical research
For any retracted article, the reason for retraction and who is instigating the retraction will be clearly stated in the Retraction notice. The retraction notice will be linked to the retracted article (which usually remains on the site) and the article will be clearly marked as retracted (including the PDF).
An article is usually only retracted at the authors’ request or by the publisher in response to an institutional investigation. It is important to note in the context of Journal of Pharmacopuncture’s publication model, that ‐ as in traditional journals ‐ a retracted article is not ‘unpublished’ or ‘withdrawn’ in order for it to be published elsewhere. The reasons for retraction are usually so serious that the whole study, or large parts of it, are not appropriate for inclusion in the scientific literature anywhere. -
Removal
The removal of an article would only be undertaken where legal limitations have been placed upon the publisher, copyright holder or author(s), for example, if the article is clearly defamatory or infringes others’ legal rights, or if the article is the subject of a court order. The bibliographic information for a removed article will be retained on the site along with information regarding the circumstances that led to its removal.
Under rare circumstances, for example, if false or inaccurate data have been published that, if acted upon, pose a serious health risk, the original incorrect version(s) may be removed and a corrected version published. The reason for this partial removal would be clearly stated on the latest version. -
Editorial Note
If there is a potential, not yet resolved, problem with an article, it may be appropriate to alert readers with an Editorial Note. Such an Editorial Note may be added to the article, for example, if Journal of Pharmacopuncture receives information that research or publication misconduct might have taken place, or that there is a serious dispute between authors or between the authors and third parties. The Editorial Note will usually be posted while further investigations take place and until a more permanent solution has been found (e.g. the publication of a revised ‘corrected’ version, or a Retraction). -
Expression of Concern
In rare cases, Journal of Pharmacopuncture may decide to publish an Expression of Concern, which is linked to the problematic article, if there are serious concerns about an article but no conclusive evidence can be obtained that would unequivocally justify a Retraction. This may include:
• if there is inconclusive evidence of research or publication misconduct
• there is evidence that there are problems with the article, but the authors’ institution will not investigate the case
• an investigation into alleged misconduct has not been impartial or conclusive
DOI : 10.3831/KPI.CrossMark.Policy
Journal Info

Editorial Office
Most Read / Downloaded
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Original Article2021-06-30
Quality Control of Pharmacopuncture: A Comparative Study of Good Manufacturing Practice and External Herbal Dispensary Standards
Ji-Eun Han1, Minjung Park2, Tteul-E-Bom An3, Jong-Hyun Park4, Danny Oh5, Kyeong Han Kim6*, Soo-Hyun Sung1*J Pharmacopuncture 2021; 24(2): 59-67 https://doi.org/10.3831/KPI.2021.24.2.59Abstract : Objectives: We aimed to compare the external herbal dispensary (EHD) evaluation criteria for pharmacopuncture and the Korea Good Manufacturing Practice (KGMP) sterile medicine standards to contribute to the establishment of quality control criteria for pharmacopuncture.Methods: We obtained the KGMP standards from the Ministry of Food and Drug Safety and the pharmacopuncture certification criteria from the Ministry of Health and Welfare of South Korea. The EHD evaluation items were classified into three categories: facilities, quality control, and validation. The evaluation items were compared with the KGMP sterile medicine criteria to determine their conformance with each other, followed by a discussion among the committee of six experts and their consensus to suggest the items to complement the EHD evaluation criteria.Results: Among the KGMP sterile medicine criteria, 44 were related to the management of the facilities, and 32 pharmacopuncture evaluation items corresponded to these KGMP items (66.7%). Fifty-eight KGMP criteria were related to quality management, and 42 pharmacopuncture evaluation items corresponded to these KGMP items (72.4%). Twenty-five KGMP sterile medicine criteria were related to validation, and 11 pharmacopuncture evaluation items corresponded to these KGMP items (44.0%). Sixteen items under the pharmacopuncture EHD criteria corresponded to the KGMP sterile medicine criteria based on the consent of the experts. Among these, 4 were related to facility management, 6 were related to quality control, and 6 were related to validation.Conclusion: For the safety and quality control of pharmacopuncture, there is a need to select the criteria for the mandatory items among the proposed pharmacopuncture-EHD criteria laws and systems to ensure that the pharmacopuncture materials are produced under the pharmacopuncture-EHD in compliance with the relevant requirements. More studies are needed to secure the safety level of pharmacopuncture materials corresponding to that of conventional medicine.
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Case Report2023-03-31
Suggested Integrative Approach for Hand Abscess with Cupping Therapy: a case study
Emad Ahmed Fathy Hussein1*, Shahira Hassan Ibrahim Negm1, Tabish Ishaq Shaikh2, Ahmed Helmy Saleh3J Pharmacopuncture 2023; 26(1): 94-98 https://doi.org/10.3831/KPI.2023.26.1.94Abstract : A forty-three-year-old male patient was diagnosed with an acute abscess in the dorsum of the right hand. On the 5th day of conventional pharmacological therapy the patient was still suffering, and was referred to the Outpatient department (OPD) to evacuate and drain the abscess and treat the edema around the area with Hijama (wet cupping therapy, WCT). The hand abscess was successfully cured within a week using an integrative approach of wet cupping therapy together with conventional drug therapy.
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Systematic Review2021-12-31
Effect of Manual Acupuncture for Mild-to-Moderate Carpal Tunnel Syndrome: A Systematic Review
Jeong Ho Huh1†, Hye In Jeong2†, Kyeong Han Kim3,4*J Pharmacopuncture 2021; 24(4): 153-164 https://doi.org/10.3831/KPI.2021.24.4.153Abstract : Objectives: Despite the low cost and high accessibility of manual acupuncture (MA) treatments for the carpal tunnel syndrome (CTS), this intervention has not been uniformly evaluated in systematic reviews (SR), and no SR has evaluated MA monotherapy for CTS. This review was conducted to summarize the findings and undertake a quality assessment of randomized controlled trials (RCTs) of acupuncture treatment methods for mild-tomoderate CTS to identify clinical evidence for the use of MA in CTS.Methods: We searched five databases for articles on relevant RCTs that were published until June 2021 without imposing specific restrictions, such as age or sex, on CTS patients. RCTs that evaluated MA were included without any restriction on comparator interventions. Measurement tools for evaluating pain reduction and functional improvement or for evaluating efficacy using electrophysiological indicators were included as outcome measures.Results: We included seven RCTs, of which three studies reported both post-treatment improvement effects and statistical significance using p-values for all outcomes. Five studies reported statistically significant intergroup differences (p-values for all outcomes) in posttreatment improvement. None of the studies reported severe adverse effects of MA. In all of the RCTs, the reporting rates of the 2c, 2a, and 6a items of STRICTA 2010 were 14%, 29%, and 29%, respectively. PC7 (Daereung) was used to treat CTS in all of the included studies.Conclusion: MA can be used for CTS treatment without serious adverse effects. PC7 was the most commonly used acupoint. In order to ensure objective and reliable reporting, accurate standardization of acupuncture treatment methods acupoint terms should be undertaken in future RCTs.
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Systematic Review2021-06-30
Effect of Complementary Medicine on Pain Relief and Wound Healing after Cesarean Section: A Systematic Review
Azin Niazi1, Maryam Moradi2*, Vahid Reza Askari3, Neda Sharifi4J Pharmacopuncture 2021; 24(2): 41-53 https://doi.org/10.3831/KPI.2021.24.2.41Abstract : Objectives: Cesarean sections are one of the common surgical procedures around the world. Management of cesarean section side effects, including pain, hematoma, delayed wound healing, is of particular importance in maintaining maternal health and ability to care for the baby. The tendency to use complementary medicine strategies is on the rise because of the easy treatment with low side effects. The purpose of this study was to systematically review the efficacy and safety of clinical trials performed in Iran and worldwide on the effect of complementary medicine on pain relief and wound healing after cesarean section.Methods: PRISMA checklist was followed to prepare the report of this systematic review. The search process was carried out on databases on databases of Magiran, SID, Iran Medex, Scopus, Pub Med, Science direct, Medline and Cochrane library using keywords of cesarean, pain, wound healing, Herbal medicine, acupressure, massage, complementary medicine and their Persian equivalent and all possible combinations, from inception until February 2020. We used the Jadad scale to assess the quality of the searched articles. According to the Jadad scale, the articles with a score of at least 3 were included in the study.Results: Finally, 28 clinical trials (with a sample size of 3,245) scored at least 3 on the Jadad scale were included into the analysis. This article reviewed 13 articles on medicinal herbs, 4 articles on massage, 1 article on reflexology, 2 articles on acupressure.Conclusion: According to the present review, the use of medicinal herbs was the most common method of complementary medicine in pain relief and wound healing after cesarean section.
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Review Article2021-09-30
Literature Review on Korean Medicine Treatment for Alopecia
Seul Woo Leem1†, Min Kyeong Kim1†, Seo Lim Ko1, Hye In Jeong2, Kyeong Han Kim3,4*J Pharmacopuncture 2021; 24(3): 93-106 https://doi.org/10.3831/KPI.2021.24.3.93Abstract : This study aimed to analyze the use of Korean medicine treatments for alopecia in among clinical studies. We identified and analyzed 22 studies from Korean databases; Oriental Medicine Advanced Searching Integrated System (OASIS), Science ON, Korean Studies Information Service System (KISS), and Research Information Sharing Service (RISS) and international database; PubMed. We analyzed the Korean medical treatment in each case and determined the tendency to use each intervention. We analyzed 1,464 patients from 22 selected studies. Herbal medicine, acupuncture, external medicine or products, pharmacopuncture, and phototherapy were used for alopecia treatment. The herbal medicines mainly used to treat alopecia were Gagam Cheongyoung-tang, Gagam Hwajung-hwan, and Yukmijihwang-tang·hwan. The acupoints primarily used were GV20, EX-HN1, GB5, KI3, PC6, ST36, GV22, and A-shi. The most commonly used pharmacopuncture therapies were Hwangryunhaedoktang (HH), Carthami Fructus (CF), Bee Venom (BV), and Hominis placenta (HP). The Korean medical treatment for alopecia improved the condition of patients. However, seven studies reported the occurrence of side effects such as pruritus, dazed, drowsiness, headache, pain, and diarrhea. This study shows the potential of Korean medicine for the treatment of alopecia. Further studies with a large sample size and long-term follow-up are warranted to establish the primary treatment guidelines and objective out-come measures for alopecia.
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Original Article2021-06-30
Regulatory Effect of Cannabidiol (CBD) on Decreased β-Catenin Expression in Alopecia Models by Testosterone and PMA Treatment in Dermal Papilla Cells
Yoon-Jong Park1, Jae-Min Ryu1, Han-Heom Na1,2, Hyun-Suk Jung2,3, Bokhye Kim2, Jin-Sung Park4, Byung-Soo Ahn4,5, Keun-Cheol Kim1,2*J Pharmacopuncture 2021; 24(2): 68-75 https://doi.org/10.3831/KPI.2021.24.2.68Abstract : Objectives: The hair follicle is composed of more than 20 kinds of cells, and mesoderm derived dermal papilla cells and keratinocytes cooperatively contribute hair growth via Wnt/β-catenin signaling pathway. We are to investigate β-catenin expression and regulatory mechanism by CBD in alopecia hair tissues and dermal papilla cells. Methods: We performed structural and anatomical analyses on alopecia patients derived hair tissues using microscopes. Pharmacological effect of CBD was evaluated by β-catenin expression using RT-PCR and immunostaining experiment. Results: Morphological deformation and loss of cell numbers in hair shaft were observed in alopecia hair tissues. IHC experiment showed that loss of β-catenin expression was shown in inner shaft of the alopecia hair tissues, indicating that β-catenin expression is a key regulatory function during alopecia progression. Consistently, β-catenin expression was decreased in testosterone or PMA treated dermal papilla cells, suggesting that those treatments are referred as a model on molecular mechanism of alopecia using dermal papilla cells. RT-PCR and immunostaining experiments showed that β-catenin expression was decreased in RNA level, as well as decreased β-catenin protein might be resulted from ubiquitination. However, CBD treatment has no changes in gene expression including β-catenin, but the decreased β-catenin expression by testosterone or PMA was restored by CBD pretreatment, suggesting that potential regulatory effect on alopecia induction of testosterone and PMA. Conclusion: CBD might have a modulating function on alopecia caused by hormonal or excess of signaling pathway, and be a promising application for on alopecia treatment.
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