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Researcher's Ethics

Journal of Pharmacopuncture Ethical Approval

  • Article 1. Research Ethics Rules for Authors

    Section.1.1. No Copying, Forging and Falsification

    (1)  Authors should not falsely claim that they have conducted research when they have not. Other researchers' academic achievements can be used for reference, including the original sources. Presenting other researchers' research as your own constitutes plagiarism.
    (2)  Faking research data, manipulating research procedures, changing and deleting arbitrarily are banned as there could affect the research outcomes.

    Section.1.2. Publication Contribution

    (1)  Authors are recognized for their own research and assume responsibility for the contents of their papers.
    (2)  Authors and papers should be listed based on their contributions to the research. Being in certain positions cannot be counted as co-authors, first authors, or corresponding authors. Not recognizing any contributions in any forms is not justified. When the levels of contributions are not big, gratitude comes in the form of a footnote or a preface. Or, it is indicated separately in the Acknowledgement.

    Section.1.3. Previous Publication or Duplicate Submission

    • The Editor assumes that all authors listed in a manuscript have agreed with the following policy of Journal of Pharmacopuncture and are responsible for the whole content on submission of manuscripts. Authors should not submit articles previously published or in press or under review. Submitting the same papers to other similar journals is not allowed. Using parts of previously published papers for publication requires consents from the publishers.
    • If a new author is added or an author is deleted after the submission, the corresponding author is responsible to ensure that the authors concerned are aware of and agree with the changes. Journal of Pharmacopuncture has no responsibility for such changes.

    Section.1.4. Citation and Reference

    (1)  Use of academic data should be clearly stated, and its sources should be disclosed in the paper unless it is shared knowledge. Information obtained through personal discussion can be used with consent from the provider of the information.
    (2)  When using other people's papers for reference or opinion, the details can be written in a footnote, indicating which part of the research is cited from other people's papers and showing the authors' own ideas, arguments and interpretations.
    (3)  If the material is not disclosed, the author should obtain permission from the copyright holder to cite the material. Also, editorial office can request confirmation.

    Section.1.5. Authorship

    • Authorship credit should be based on 1) substantial contributions to conception and design, acquisition of data, and/or analysis and interpretation of data; 2) drafting the article or revising it critically for important intellectual content; 3) final approval of the version to be published; and 4) agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved. Every author should meet all of these four conditions. After the initial submission of a manuscript, any changes whatsoever in authorship (adding author(s), deleting author(s), or re-arranging the order of authors) must be explained by a letter to the editor from the authors concerned. This letter must be signed by all authors of the paper. Copyright assignment must also be completed by every author.
    (1)  Corresponding author and first author: Journal of Pharmacopuncture does not allow multiple corresponding authors for one article. Only one author should correspond with the editorial office and readers for one article. Journal of Pharmacopuncture does accept notice of equal contribution for the first author when the study was clearly performed by co-first authors.
    (2)  Correction of authorship after publication: Journal of Pharmacopuncture does not correct authorship after publication unless a mistake has been made by the editorial staff. Authorship may be changed before publication but after submission when an authorship correction is requested by all of the authors involved with the manuscript.

    Section.1.6. Human Rights in Experiments

    • For research on humans, the study protocol must be reviewed and approved by the appropriate Institutional Review Board (IRB). The IRB approval number should be provided (e.g. Approval No. 2019013). In addition, informed consent must be obtained from all subjects at the time they are enrolled. Editorial Board and Reviewer is able to reject manuscripts for concerning of ethical or human welfare.

    Section.1.7. Animal Rights in Experiments

    • For animal experimentation, the procedures used and the care of animals should be approved by the Institutional Animal Care and Use Committee (IACUC) of one of the authors' institution(s), and the approval number should be provided (e.g. Approval No. 2019011). Additionaly, pathogens involving research requiring a high degree of biosafety should pass the review of a relevant committee (e.g., an Institutional Biosafety Committee). Editorial Board and Reviewer is able to reject manuscripts for concerning of ethical or human welfare.
  • Article.2. Research Ethics Rules for Editorial Board Members

    Section.2.1. Roles

    • The Editorial Board members assume the responsibility for deciding whether to publish submitted papers. They need to respect the authors' individualities.

    Section.2.2. No Bias

    • All submissions should be treated equally and evaluated fairly based on the quality of the manuscripts and by the rules. No special treatment is given for authors' gender, age, affiliation, or personal connection.

    Section.2.3. Review

    • The Editorial Board members should commission reviewers who are well knowledgeable in their areas with good judgment. Persons with personal ties to the authors should not be recommended as reviewers. Reviewers who are hostile towards authors should not be considered as reviewers. When review results are significantly different from reviewer to reviewer, the Editorial Board can seek advice from outside experts with deep knowledge of the field for a final decision.

    Section.2.4. Confidentiality Disclosure

    • Until the final decision of acceptance is made, no information about the authors or the manuscript can be released.

    Section.2.5. Duty for Report

    • If any complaints are made about the review of a manuscript to the Editorial Board, it should be reported to the Ethics Board immediately.
  • Article.3. Research Ethics Rules for Reviewers

    Section.3.1. Review Period and Decline of Review

    • Reviewers are required to evaluate papers commissioned by the Editorial Board within a certain period of time set for review. They need to inform the Editorial Board of the review results. If the reviewer thinks he or she will not be able to serve as a reviewer for some reasons, he or she should notify the Editorial Board of his or her inability to do the review.

    Section.3.2. No bias

    • Reviewers are required to review manuscripts fairly and objectively. They also should not allow any personal beliefs or personal ties to disrupt the review process. Rejecting manuscripts because they are against personal beliefs or interpretations without properly presenting sensible reasons is not acceptable. Reviewing without thoroughly reading the manuscripts is also not acceptable.

    Section.3.3. Notification

    • Reviewers should notify the Editorial Board when they find that papers they are reviewing have been published in other journals or are under review. Also, any problems concerning the papers should be addressed to the Editorial Board.

    Section.3.4. Making Reviewers' Comments

    • Reviewers should respect the authors' individualities. While expressing opinions on manuscripts in an evaluation form, the reviewers need to explain why the paper needs corrections. Reviewers' comments should be expressed positively. Belittling or insulting authors is not allowed.

    Section.3.5. Confidentiality Disclosure

    • Information on assigned papers should be kept confidential by reviewers. Showing the papers to or consulting with someone else is not desirable unless the reviewers are seeking advice for review. Citing any passages in whole or part from the manuscript before publication is not allowed.
  • Article.4. Standards of Ethics and Guidelines

Journal Info

Journal of Pharmacopuncture
Vol.27 No.4
December, 2024

pISSN 2093-6966
eISSN 2234-6856
Quarterly

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  • Case Report2023-03-31

    Suggested Integrative Approach for Hand Abscess with Cupping Therapy: a case study

    Emad Ahmed Fathy Hussein1*, Shahira Hassan Ibrahim Negm1, Tabish Ishaq Shaikh2, Ahmed Helmy Saleh3
    J Pharmacopuncture 2023; 26(1): 94-98 https://doi.org/10.3831/KPI.2023.26.1.94

    Abstract : A forty-three-year-old male patient was diagnosed with an acute abscess in the dorsum of the right hand. On the 5th day of conventional pharmacological therapy the patient was still suffering, and was referred to the Outpatient department (OPD) to evacuate and drain the abscess and treat the edema around the area with Hijama (wet cupping therapy, WCT). The hand abscess was successfully cured within a week using an integrative approach of wet cupping therapy together with conventional drug therapy.

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  • Review Article2023-03-31

    A Review of Clinical and Preclinical Studies on the Therapeutic Potential of Black Seeds (Nigella sativa) in the Management of Polycystic Ovarian Syndrome (PCOS)

    Rajkapoor Balasubramanian1*, Naina Mohamed Pakkir Maideen2, Sudha Muthusamy3, Mirunalini Gobinath4
    J Pharmacopuncture 2023; 26(1): 1-9 https://doi.org/10.3831/KPI.2023.26.1.1

    Abstract : Objectives: Polycystic ovary syndrome (PCOS) is a condition that occurs frequently among women of reproductive age and is a polygenic, multifactorial, endocrine, and metabolic disorder. PCOS is becoming more common as a result of risk factors such as current lifestyle, overnutrition, and stress. The use of traditional herbal medicine is higher among the global population. Hence, this review article focuses on the potential of Nigella sativa to manage women with PCOS.Methods: A literature search was carried out using databases including Medline, Google Scholar, EBSCO, Embase, and Science Direct, as well as reference lists, to identify relevant publications that support the use of N. sativa in the management of women with PCOS.Results: Several clinical and preclinical studies have demonstrated that the major bioactive constituent of black seed (N. sativa), thymoquinone, has potential for managing women with PCOS. Moreover, N. sativa may help to manage oligomenorrhea and amenorrhea in women with PCOS through its anti-inflammatory and antioxidant properties.Conclusion: N. sativa has potential for use as a herbal medicine for managing women with PCOS as an integrative medicine along with traditional and modern medicine in conjunction with calorie restriction and regular exercise.

    Abstract
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  • Original Article2024-06-30

    The Effect of the Combination of Ginseng, Tribulus Terrestris, and L-arginine on the Sexual Performance of Men with Erectile Dysfunction: a randomized, double-blind, parallel, and placebo-controlled clinical trial

    Reza Tahvilian1, Mohammad Amin Golesorkhi2, Farajollah Parhoudeh3, Fatemeh Heydarpour4, Hossein Hosseini5, Hojjat Baghshahi5*, Hossein Akbari6, Mohammad Reza Memarzadeh5, Mehdi Mehran5, Hosna Bagheri2
    J Pharmacopuncture 2024; 27(2): 82-90 https://doi.org/10.3831/KPI.2024.27.2.82

    Abstract : Objectives: Nitric oxide is the most important mediator of penile erection after the onset of sexual excitement. It activates cyclic guanosine monophosphate (cGMP), increasing penile blood flow. Most pharmaceutical medications prevent enzyme phosphodiesterase type 5 (PDE-5) from breaking down cGMP, thus keeping its level high. However, due to the adverse effects of pharmacological therapies, herbal drugs that improve sexual function have gained attention recently. This study aimed to investigate the combined effects of ginseng, Tribulus terrestris, and L-arginine amino acid on the sexual performance of individuals with erectile dysfunction (ED) using the 5-item version of the International Index of Erectile Function (IIEF-5) questionnaire. Methods: Over three months, 98 men with erectile dysfunction were randomly assigned to receive either 500 mg of herbal supplements or placebo pills. Each herbal tablet contained 100 mg of protodioscin, 35 mg of ginsenosides, and 250 mg of L-arginine. Results: The results showed that the changes in the average scores of ILEF-5 within each group before and after the intervention indicated that all parameters related to the improvement of sexual function in patients with erectile dysfunction improved in the herbal treatment group (p < 0.001). The herbal group significantly improved IIEF-5 scores in non-diabetics (p < 0.05). However, there was no significant difference in the changes of IIEF-5 scores between the two intervention and control groups in diabetic patients. Conclusion: In conclusion, ginseng, Tribulus terrestris, and L-arginine have properties that increase energy and strengthen sexual function, making them suitable for patients with sexual disorders.

    Abstract
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  • Review Article2023-03-31

    A Review of Clinical and Preclinical Studies on the Therapeutic Potential of Black Seeds (Nigella sativa) in the Management of Polycystic Ovarian Syndrome (PCOS)

    Rajkapoor Balasubramanian1*, Naina Mohamed Pakkir Maideen2, Sudha Muthusamy3, Mirunalini Gobinath4
    J Pharmacopuncture 2023; 26(1): 1-9 https://doi.org/10.3831/KPI.2023.26.1.1

    Abstract : Objectives: Polycystic ovary syndrome (PCOS) is a condition that occurs frequently among women of reproductive age and is a polygenic, multifactorial, endocrine, and metabolic disorder. PCOS is becoming more common as a result of risk factors such as current lifestyle, overnutrition, and stress. The use of traditional herbal medicine is higher among the global population. Hence, this review article focuses on the potential of Nigella sativa to manage women with PCOS.Methods: A literature search was carried out using databases including Medline, Google Scholar, EBSCO, Embase, and Science Direct, as well as reference lists, to identify relevant publications that support the use of N. sativa in the management of women with PCOS.Results: Several clinical and preclinical studies have demonstrated that the major bioactive constituent of black seed (N. sativa), thymoquinone, has potential for managing women with PCOS. Moreover, N. sativa may help to manage oligomenorrhea and amenorrhea in women with PCOS through its anti-inflammatory and antioxidant properties.Conclusion: N. sativa has potential for use as a herbal medicine for managing women with PCOS as an integrative medicine along with traditional and modern medicine in conjunction with calorie restriction and regular exercise.

    Abstract
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  • Review Article2023-06-30

    A Review on Acupuncture Efficiency in Human Polycystic Ovary/Ovarian Syndrome

    Natália M. de Oliveira1,2*, Jorge Machado1,2,3, Lara Lopes1,2, Maria Begoña Criado2,4
    J Pharmacopuncture 2023; 26(2): 105-123 https://doi.org/10.3831/KPI.2023.26.2.105

    Abstract : Objectives: Human Polycystic Ovary/Ovarian Syndrome (PCOS), a frequent endocrine pathophysiology among women of fertile age, is associated with woman’s lifespan endocrine, metabolic and psychological implications. Long-term usage side effects of allopathic strategies and their low efficacy made complementary medicine treatments a relevant subject for these patients. The main aim of this work is to review the efficiency of the acupuncture treatment reported in the latest studies on literature regarding PCOS patients.Methods: A comprehensive literature search, in English language, about the use of acupuncture on the management of PCOS, was conducted in October 2020 using EBSCO, Cochrane, PubMed, Medline, Embase, databases for randomised and non-randomised controlled trials between 2015 and 2020 (09/2015-10/2020), following the PRISMA protocol.Results: This research led us to an analysis, according to PICOS, of six final papers selected among 178 in total. The articles addressed distinct aspects of the PCOS condition, diverse acupuncture techniques and different main and secondary outcomes in agreement to the respective main objective. According to this review, acupuncture seems to be useful for the treatment of this debilitating and chronic health condition which affects millions of women worldwide, many of them part of the workforce in their community.Conclusion: Despite of the display of these positive results addressing acupuncture treatments to manage PCOS major symptoms - whether they are reproductive, metabolic, or mental health features - more research is urgent. Randomized, double blinded controlled trials with improved quality design and following STRICTA and/or CONSORT recommendations are necessary to engage acupuncture as a standardized and scientific validated technique in PCOS condition.

    Abstract
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  • Review Article2024-06-30
    JoP

    Indigo Naturalis in Inflammatory Bowel Disease: mechanisms of action and insights from clinical trials

    Hyeonjin Kim, Soohyun Jeong, Sung Wook Kim, Hyung-Jin Kim, Dae Yong Kim, Tae Han Yook, Gabsik Yang*
    J Pharmacopuncture 2024; 27(2): 59-69 https://doi.org/10.3831/KPI.2024.27.2.59

    Abstract : This study investigates the therapeutic potential of Indigo Naturalis (IN) in treating a Inflammatory Bowel Disease (IBD). The objective is to comprehensively examine the effects and pharmacological mechanisms of IN on IBD, assessing its potential as an novel treatment for IBD. Analysis of 11 selected papers is conducted to understand the effects of IN, focusing on compounds like indirubin, isatin, indigo, and tryptanthrin. This study evaluates their impact on Disease Activity Index (DAI) score, colon length, mucosal damage, and macrophage infiltration in Dextran Sulfate Sodium (DSS)-induced colitis mice. Additionally, It investigate into the anti-inflammatory mechanisms, including Aryl hydrocarbon Receptor (AhR) pathway activation, Nuclear Factor kappa B (NF-κB)/nod-like receptor family pyrin domain containing 3 (NLRP3)/Interleukin 1 beta (IL-1β) inhibition, and modulation of Toll-like receptor 4 (TLR4)/myeloid differentiation primary response 88 (MYD88)/NF-κB and Mitogen Activated Protein Kinase (MAPK) pathways. Immunomodulatory effects on T helper 17 (Th17)/regulatory T cell (Treg cell) balance and Glycogen synthase kinase-3 beta (GSK3-β) expression are also explored. Furthermore, the study addresses the role of IN in restoring intestinal microbiota diversity, reducing pathogenic bacteria, and increasing beneficial bacteria. The findings reveal that IN, particularly indirubin and indigo, demonstrates significant improvements in DAI score, colon length, mucosal damage, and macrophage infiltration in DSS-induced colitis mice. The anti-inflammatory effects are attributed to the activation of the AhR pathway, inhibition of inflammatory pathways, and modulation of immune responses. These results exhibit the potential of IN in IBD treatment. Notably, the restoration of intestinal microbiota diversity and balance further supports its efficacy. IN emerges as a promising and effective treatment for IBD, demonstrating anti-inflammatory effects and positive outcomes in preclinical studies. However, potential side effects necessitate further investigation for safe therapeutic development. The study underscores the need for future research to explore a broader range of active ingredients in IN to enhance therapeutic efficacy and safety.

    Abstract
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